2011
DOI: 10.1002/ajim.21012
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Acute respiratory effects in firefighters

Abstract: Acute exposure to fire smoke induces acute neutrophilic airway and long-lasting systemic inflammation in healthy firefighters in the absence of bronchial hyperresponsiveness.

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Cited by 33 publications
(30 citation statements)
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References 48 publications
(69 reference statements)
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“…IL-8 is a neutrophil attractant, thus an association may be expected. This is in contrast to the findings in firefighters after exposure (Greven et al 2012), where an increase of both neutrophils and IL-8 in serum was noticed 24 h after firefighting. The reason for this discrepancy may be the kind or the intensity of exposure.…”
Section: Discussioncontrasting
confidence: 99%
“…IL-8 is a neutrophil attractant, thus an association may be expected. This is in contrast to the findings in firefighters after exposure (Greven et al 2012), where an increase of both neutrophils and IL-8 in serum was noticed 24 h after firefighting. The reason for this discrepancy may be the kind or the intensity of exposure.…”
Section: Discussioncontrasting
confidence: 99%
“…Acute airway inflammation has been described after exposure to ambient particulate matter (PM) and WTC-PM [16e18]. Greven et al [38] showed that acute exposure to fire smoke induces acute neutrophilic airway and long-lasting systemic inflammation in healthy firefighters. Serum IL-8 concentrations were higher 24 h post-exposure compared to pre-exposure and elevated levels lasted up to 3 months.…”
Section: Discussionmentioning
confidence: 99%
“…Está também descrita neste contexto a exposição a hidrocarbonetos e óxidos de nitrogénio (18) ; bem como a acroleína, formaldeído e o benzeno (21) . A inalação aguda ao fumo induz aumento da inflamação sistémica, mesmo na ausência de hiperresponsividade brônquica (20,21) (sendo esta, ainda assim, mais frequente nos atópicos) (19) . A exposição cumulativa pode implicar diminuição discreta da função pulmonar (16,21) .…”
Section: Riscos Respiratóriosunclassified