Additive manufacturing of biodegradable Zn-xMg alloys: Effect of Mg content on manufacturability, microstructure and mechanical properties

Structural and temporal dynamics analysis of zinc-based biomaterials: History, research hotspots and emerging trends

“…The composition of the alloys (such as Mg, Ag, Al, Li, copper, rare earth elements, etc.) [ 69 , [147] , [148] , [149] , [150] , [151] , [152] , [153] ], nanoreinforcing materials (such as reduced graphene oxide and nanosilicon carbide) [ 154 , 155 ], 3D configurations [ [156] , [157] , [158] ], and reducing defects such as porosity, lack of fusion, inclusions, cracks, and voids through the process are also crucial for ensuring the mechanical properties of additive manufactured Zn alloys. The addition of alloy components also shows a trend toward developing from binary alloys to ternary alloys [ 152 , 159 ].…”

Zinc-based biomaterials for bone repair and regeneration: mechanism and applications

“…The incorporation of Mg led to grain refinement but brittle phase formation. 163 An AM Zn–Li scaffold has also been fabricated successfully via L-PBF. It showed comparable mechanical properties to cancellous bones, with a compressive strength of 18.2 MPa and an elastic modulus of 298.0 MPa.…”

Research progress in degradable metal‐based multifunctional scaffolds for bone tissue engineering

“…Biocompatibility and osteogenesis of Zn Mg alloys improve with increasing Mg, but excessive Mg will reduce the electrical and mechanical properties of the alloy. 57,58 Alloys may also need to combine other metal elements, such as silver (Zn-0.04Mg-2AG), to balance their mechanical performance and biological functions, thereby giving alloy antibacterial capabilities. 59 The degradation and bone regeneration after implantation of Zn-2Ag-0.04Mg scaffold into the femur of New Zealand rabbits could be observed, and no abnormalities were found in hematoxylin and eosin (HE) staining of the liver, kidney, and heart.…”

“…For example, a zinc magnesium (ZN‐1% wt Mg) alloy constructed using the LPBF technique exhibited the highest compressive strength and Young's modulus, which are 19.1–41.3 MPa and 0.11–0.65 GPa, respectively. Biocompatibility and osteogenesis of Zn Mg alloys improve with increasing Mg, but excessive Mg will reduce the electrical and mechanical properties of the alloy 57,58 . Alloys may also need to combine other metal elements, such as silver (Zn‐0.04Mg‐2AG), to balance their mechanical performance and biological functions, thereby giving alloy antibacterial capabilities 59 .…”