Adenoidal Disease and Chronic Rhinosinusitis in Children—Is There a Link?

Bulfamante, Antonio Mario; Saibene, Alberto Maria; Felisati, Giovanni; Rosso, Cecilia; Pipolo, Carlotta

doi:10.3390/jcm8101528

Cited by 22 publications

(21 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The pathogenesis of AH is not yet clear, but it is related to many factors, such as smoking, seasonal allergies, and respiratory infections [ 1 ]. The relationship between AH and rhinosinusitis has been confirmed in previous studies, and therapies aimed at AH effectively treat rhinosinusitis [ 2 , 3 ]. However, the information concerning the relationship between AH and allergic rhinitis (AR) is not consistent.…”

Section: Introductionmentioning

confidence: 68%

Detecting epidemiological relevance of adenoid hypertrophy, rhinosinusitis, and allergic rhinitis through an Internet search

et al. 2021

Eur Arch Otorhinolaryngol

View full text Add to dashboard Cite

Purpose This study aimed to detect the epidemiological relevance between adenoid hypertrophy (AH) and rhinosinusitis, and AH and allergic rhinitis (AR) through an Internet search. Methods Internet search query data from January 2011 to December 2019 in China were retrieved from the Baidu Index (BI). Spearman’s correlation coefficients were used to detect the correlation among the search volumes of AH, rhinosinusitis, and AR. We also collected search data from the first 5 months of 2020, when quarantine was implemented in China due to the coronavirus disease 2019 epidemic. Then, we compared the search data to those obtained during the same period in 2019 to assess the effects of isolation on AH and AR. Results Statistically significant relevance was found between the search variations of AH and rhinosinusitis during 2011–2019 ( R = 0.643, P < 0.05). However, the relationship between AH and AR was weak ( R = − 0.239, P < 0.05) and that between rhinosinusitis and AR ( R = − 0.022, P > 0.05) was not relevant. The average monthly search volume of AH and rhinosinusitis had a strong correlation ( R = 0.846, P < 0.01), but AH and AR and rhinosinusitis and AR were not correlated ( R = – 0.350, P > 0.05; R = – 0.042, P > 0.05, respectively). AH and rhinosinusitis search volumes decreased consistently during the first 5 months of 2020 (isolation), whereas that for AR increased during January–February. Conclusion AH had an epidemiological relationship with rhinosinusitis, which was not consistent with AR. The decrease in public gathering effectively reduced the morbidities of AH and rhinosinusitis but not those of AR.

show abstract

Section: Introductionmentioning

confidence: 68%

Detecting epidemiological relevance of adenoid hypertrophy, rhinosinusitis, and allergic rhinitis through an Internet search

et al. 2021

Eur Arch Otorhinolaryngol

View full text Add to dashboard Cite

show abstract

“…Гипертрофия глоточной миндалины наблюдается у 34-70% детей разных возрастных групп и 2,5% взрослых [47][48][49]. Обзоры литературы по ключевым словам «аденоиды» и «хронический синусит» показали, что гипертрофия глоточной миндалины способствует формированию хронического риносинусита как причина назальной обструкции, препятствующая нормальной аэрации ОНП, а также как бактериальный резервуар, содержащий биопленки [47,48]. Эти факторы нарушают мукоцилиарный клиренс ОНП.…”

Section: цель работыunclassified

“…Метаанализ продемонстрировал эффективность аденоидэктомии при лечении ХРС у детей в 70%, в отличие от тонзиллэктомии [47,52]. Упорное течение ХРС у детей может быть обусловлено муковисцидозом, аллергией, первичной цилиарной дискинезией и иммунодефицитом [47,48].…”

Section: цель работыunclassified

Effect of nasal cavity and nasopharynx architectonic disorders on the paranasal sinus development and sinusitis

Subbotina¹,

Kokhanov²

2020

View full text Add to dashboard Cite

The structure of the paranasal sinuses (PNS) is characterized by pronounced variability and largely depends on the state of the intranasal architectonics, the violation of which may be a predisposing factor for the development of sinusitis. Leading among the disturbances in the architectonics of the nasal cavity and nasopharynx are the nasal septum deviation (NSD), concha bullosa (CB), hypertrophy of the inferior turbinates and pharyngeal tonsil. This review presents an analysis of modern data on the influence of the architectonics of the nasal cavity and nasopharynx on the development of PNS and the formation of inflammatory processes in them. Sources of information - databases Medline, Pubmed, Cochrane, E-library from 2004 to 2019. The search was carried out by keywords. Criteria for inclusion of articles in the review: assessment of multispiral computed tomography of SNP of patients in axial and coronary projections, presence of a control group, sample size of more than 50 people. In the presented review, it is noted that types 3 and 5 of DNP according to the classification of R. Mladina, along with contralateral CB and adenoids, can be predictors of the development of sinusitis. Information about the side of sinusitis formation in relation to the direction of the deformity of the nasal septum, about the effect of other violations of the architectonics of the nasal cavity on sinusitis and the size of the SNP remains controversial. The reasons for the contradictions are the use of different classifications of DNP, the underestimation of the complexes of anatomical anomalies and the mechanisms of aerodynamics of the sinuses, which determine the greater dependence of the volume and ventilation of the sinuses on expiration than on inspiration. Taking these positions into account, the question of the influence of the architectonics of the nasal cavity on the development of the paranasal sinuses and the formation of the inflammatory process in them requires further study.

show abstract

“…The adenoids are lobulated masses of lymphoid tissue which is located in an axial position of the upper respiratory tract ( 1 ). Adenoid hypertrophy (AH) is common in children, due to chronic inflammation that leads to the proliferation of adenoid lymphoid tissue ( 2 , 3 ). Furthermore, the adenoids considered as an important bacterial reservoir in children which have a significant role in the development of infectious diseases according to the alteration of the host immune system ( 4 ).…”

Section: Introductionmentioning

confidence: 99%

Biofilm formation and molecular analysis of intercellular adhesion gene cluster (icaABCD) among Staphylococcus aureus strains isolated from children with adenoiditis

Ghaioumy¹,

Tabatabaeifar²,

Mozafarinia³

et al. 2021

IJM

View full text Add to dashboard Cite

Background and Objectives: It is well known that Staphylococcus aureus biofilm plays an important role in adenoiditis and biofilm resistance frequently results in failure of therapy. The goal of this study was to evaluate the biofilm production of S. aureus isolates obtained from adenoid specimens and assess the relationship between biofilm formation ability and ica operon genes. Materials and Methods: A total of 112 adenoid samples were obtained from patients under 15 years old with adenoid hypertrophy. All S. aureus isolates were initially identified by standard microbiological tests and amplification of nuc by polymerase chain reaction (PCR) technique. Biofilm formation of S. aureus isolates was evaluated and icaADBC genes were detected by PCR technique. Results: There were 46 isolates (41%) identified as S. aureus. The ability to produce biofilm was detected among total S. aureus isolates. Molecular study of ica operon revealed that 2 (6.3%) and 19 (59.4%) isolates carried icaA and icaD, respec- tively. The prevalence of icaA + icaD was seen among 11 (34.4%) S. aureus isolates, while icaC and icaB were not detected. Conclusion: Our findings indicated that icaABCD operon are associated with biofilm formation in S. aureus isolates, how- ever the absence of these genes may not necessarily exclude this property.

show abstract

Adenoidal Disease and Chronic Rhinosinusitis in Children—Is There a Link?

Cited by 22 publications

References 38 publications

Detecting epidemiological relevance of adenoid hypertrophy, rhinosinusitis, and allergic rhinitis through an Internet search

Detecting epidemiological relevance of adenoid hypertrophy, rhinosinusitis, and allergic rhinitis through an Internet search

Effect of nasal cavity and nasopharynx architectonic disorders on the paranasal sinus development and sinusitis

Biofilm formation and molecular analysis of intercellular adhesion gene cluster (icaABCD) among Staphylococcus aureus strains isolated from children with adenoiditis

Contact Info

Product

Resources

About