Adenoma detection with Endocuff colonoscopy versus conventional colonoscopy: a multicentre randomised controlled trial

Doorn, SC van; Vlugt, Manon van der; Depla, A.C.T.M.; Wientjes, C.A.; Mallant-Hent, RC; Siersema, PD; Tytgat, Kmaj; Tuynman, H. A. R. E.; Kuiken, SD; Houben, G.M.P.; Stokkers, P.C.F.; Moons, Lmg; Bossuyt, P. M. M.; Fockens, Paul; Mundt, Marco W.; Dekker, Evelien

doi:10.1136/gutjnl-2015-310097

Cited by 116 publications

(143 citation statements)

References 38 publications

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“…There were three studies that evaluated the cecal intubation time[16,17,21] (Table 1). The reported average cecal intubation times between the EC group were relatively similar to the standard colonoscopy group, with EC group being between 7.0 to 11.7 min compared to 8.3 to 10.7 min in the standard colonoscopy group.…”

Section: Resultsmentioning

confidence: 99%

“…Results remained statistically significant, favoring higher adenoma detection rate in the EC group compared to the standard colonoscopy (OR = 1.42 95%CI: 1.18-1.72, I 2 = 50%, P < 0.01). Furthermore, if only indexing randomized control trials in the meta-analysis[14,15,17,19] there remains statistically significant higher adenoma detection rate in the EC compared to the standard colonoscopy group (OR = 1.33 95%CI: 1.01-1.76; I 2 = 66%, P = 0.03).…”

Section: Resultsmentioning

confidence: 99%

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Use of the Endocuff during routine colonoscopy examination improves adenoma detection: A meta-analysis

Chin¹,

Karnes²,

Jamal³

et al. 2016

WJG

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AIMTo perform meta-analysis of the use of Endocuff during average risk screening colonoscopy.METHODSScopus, Cochrane databases, MEDLINE/PubMed, and CINAHL were searched in April 2016. Abstracts from Digestive Disease Week, United European Gastroenterology, and the American College of Gastroenterology meeting were also searched from 2004-2015. Studies comparing EC-assisted colonoscopy (EAC) to standard colonoscopy, for any indication, were included in the analysis. The analysis was conducted by using the Mantel-Haenszel or DerSimonian and Laird models with the odds ratio (OR) to assess adenoma detection, cecal intubation rate, and complications performed.RESULTSNine studies (n = 5624 patients) were included in the analysis. Compared to standard colonoscopy, procedures performed with EC had higher frequencies for adenoma (OR = 1.49, 95%CI: 1.23-1.80; P = 0.03), and sessile serrated adenomas detection (OR = 2.34 95%CI: 1.63-3.36; P < 0.001). There was no significant difference in cecal intubation rates between the EAC group and standard colonoscopy (OR = 1.26, 95%CI: 0.70-2.27, I2 = 0%; P = 0.44). EAC was associated with a higher risk of complications, most commonly being superficial mucosal injury without higher frequency for perforation.CONCLUSIONThe use of an EC on colonoscopy appears to improve pre-cancerous polyp detection without any difference in cecal intubation rates compared to standard colonoscopy.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Use of the Endocuff during routine colonoscopy examination improves adenoma detection: A meta-analysis

Chin¹,

Karnes²,

Jamal³

et al. 2016

WJG

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show abstract

“…A recently published Japanese-simulated randomized study involving an anatomic colorectal model further supports the benefit of EndoCuff application for ADR improvement [78]. On the other hand, in one recently published large randomized controlled trial from the Netherlands, the use of EndoCuff was not associated with a higher ADR [79]. In that study, 1,063 patients were randomized either to EndoCuff or standard colonoscopy.…”

Section: Technical Aspectsmentioning

confidence: 99%

Endoscopic Improvement of the Adenoma Detection Rate during Colonoscopy - Where Do We Stand in 2015?

Floer

Meister²

2016

Digestion

238

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Background: The presence of colorectal adenomas is considered a major risk factor for colorectal cancer development. The implementation of screening colonoscopy programs in the Western world has led to a substantial reduction of colorectal cancer death. Many efforts have been made to reduce the adenoma miss rates by the application of new endoscopic devices and techniques for better adenoma visualization. Summary: This special review gives the readership an overview of current endoscopic innovations that can aid in the increase of the adenoma detection rate (ADR) during colonoscopy. These innovations include the use of devices like EndoCuff® and EndoRings® as well as new technical equipment like third-eye endoscope® and full-spectrum endoscopy (FUSE®). Key Message: Technical improvements and newly developed accessories are able to improve the ADR. However, additional costs and a willingness to invest into potentially expensive equipment might be necessary. Investigator-dependent skills remain the backbone in the ADR detection.

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“…Although all studies included both screening and diagnostic exams, an initial study showed a significant increase over a low baseline ADR with use of the Endocuff® device (35 vs. 21 %) [28]. Other investigators found no significant difference in the number of adenomas removed per patient between the Endocuff and standard exam groups, but did describe a significantly lower cecal intubation rate when using the device [29]. A third study described a higher polyp detection rate with this attachment especially in the sigmoid colon and cecum and for polyps smaller than 1 cm [30].…”

Section: Endocuff®mentioning

confidence: 93%

Can Technology Improve the Quality of Colonoscopy?

Thirumurthi

Ross

Raju

2016

Curr Gastroenterol Rep

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In order for screening colonoscopy to be an effective tool in reducing colon cancer incidence, exams must be performed in a high-quality manner. Quality metrics have been presented by gastroenterology societies and now include higher adenoma detection rate targets than in the past. In many cases, the quality of colonoscopy can often be improved with simple low-cost interventions such as improved procedure technique, implementing split-dose bowel prep, and monitoring individuals' performances. Emerging technology has expanded our field of view and image quality during colonoscopy. We will critically review several technological advances in the context of quality metrics and discuss if technology can really improve the quality of colonoscopy.

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Adenoma detection with Endocuff colonoscopy versus conventional colonoscopy: a multicentre randomised controlled trial

Abstract: http://www.trialregister.nl Dutch Trial Register: NTR3962.

Cited by 116 publications

References 38 publications

Use of the Endocuff during routine colonoscopy examination improves adenoma detection: A meta-analysis

Use of the Endocuff during routine colonoscopy examination improves adenoma detection: A meta-analysis

Endoscopic Improvement of the Adenoma Detection Rate during Colonoscopy - Where Do We Stand in 2015?

Can Technology Improve the Quality of Colonoscopy?

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