Advanced materials-integrated electrochemical sensors as promising medical diagnostics tools: A review

Nemčeková, Katarína; Labuda, Ján

doi:10.1016/j.msec.2020.111751

Cited by 76 publications

(44 citation statements)

References 330 publications

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“…Thus, it can be used as a tool for the measurement of surface coverage, as well as for concentration dependence, as seen with the biosensor shown in Figure 6 . Many recent examples are provided in the reviews in [ 16 , 17 ], which focus on medical diagnostics. The importance of nanocomposite transducers and their evaluation and application employing redox probes is highlighted in [ 18 ], which also considers non-faradaic impedance sensing (see Section 4.2 ).…”

Section: Eis As a Sensing Techniquementioning

confidence: 99%

Electrochemical Impedance Spectroscopy in the Characterisation and Application of Modified Electrodes for Electrochemical Sensors and Biosensors

Brett

2022

Molecules

112

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Electrochemical impedance spectroscopy is finding increasing use in electrochemical sensors and biosensors, both in their characterisation, including during successive phases of sensor construction, and in application as a quantitative determination technique. Much of the published work continues to make little use of all the information that can be furnished by full physical modelling and analysis of the impedance spectra, and thus does not throw more than a superficial light on the processes occurring. Analysis is often restricted to estimating values of charge transfer resistances without interpretation and ignoring other electrical equivalent circuit components. In this article, the important basics of electrochemical impedance for electrochemical sensors and biosensors are presented, focussing on the necessary electrical circuit elements. This is followed by examples of its use in characterisation and in electroanalytical applications, at the same time demonstrating how fuller use can be made of the information obtained from complete modelling and analysis of the data in the spectra, the values of the circuit components and their physical meaning. The future outlook for electrochemical impedance in the sensing field is discussed.

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Section: Eis As a Sensing Techniquementioning

confidence: 99%

Electrochemical Impedance Spectroscopy in the Characterisation and Application of Modified Electrodes for Electrochemical Sensors and Biosensors

Brett

2022

Molecules

112

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“…The growing need for biocompatible, disposable, lightweight, electrochemical (bio)sensors and devices for laboratory as well as point-of-care (POC) diagnostics stimulate the development of electrode materials that are relatively cheap, conductive, biocompatible, and flexible [1].…”

Section: Introductionmentioning

confidence: 99%

“…For the category of flexible electrode materials that can be used in wearable sensor devices, graphene [1] is one of the most promising among other carbon materials, such as carbon nanotubes, conductive diamond [3], and diamond-like carbon.…”

Section: Introductionmentioning

confidence: 99%

Laser‐induced Graphene in Facts, Numbers, and Notes in View of Electroanalytical Applications: A Review

Muzyka

2021

Electroanalysis

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In this review, laser-induced graphene (LIG) -based electrodes are discussed by covering such essential areas, as a characterization of LIG material properties necessary for electroanalysis, including data on LIG sheet resistance, wettability, spatial resolution, electrochemical characteristics, as well as correlations of "process" -"properties" -"electroanalytical characteristics"of LIGelectrodes. Moreover, typical and innovative LIG-based electrodes designs for electroanalytical applications, including combined multi-analyte multimodal wearable sensors, interdigitated electrodes, are shown. The essential data related to LIG in electroanalysis are summarized in tables. The authors also discussed recent LIG-based electroanalytical applications. Close attention has been paid to LIG glucose sensors and biosensors.

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“…The high sensitivity and fast response time of the wearable sensors have led researchers to use them with activities related to daily life. When used as reliable diagnostic devices, these prototypes have been able to provide a linear response for wearable electrochemical [ 119 ] and strain-sensing [ 120 ] applications. Graphene, having unique electronic and chemical properties, can detect micro-movements [ 121 ] and operate as biomarkers to different kinds of ions [ 122 ].…”

Section: Graphene/pdms-based Sensorsmentioning

confidence: 99%

Integration of Different Graphene Nanostructures with PDMS to Form Wearable Sensors

Zhang

Gao

et al. 2022

Nanomaterials

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This paper presents a substantial review of the fabrication and implementation of graphene-PDMS-based composites for wearable sensing applications. Graphene is a pivotal nanomaterial which is increasingly being used to develop multifunctional sensors due to their enhanced electrical, mechanical, and thermal characteristics. It has been able to generate devices with excellent performances in terms of sensitivity and longevity. Among the polymers, polydimethylsiloxane (PDMS) has been one of the most common ones that has been used in biomedical applications. Certain attributes, such as biocompatibility and the hydrophobic nature of PDMS, have led the researchers to conjugate it in graphene sensors as substrates or a polymer matrix. The use of these graphene/PDMS-based sensors for wearable sensing applications has been highlighted here. Different kinds of electrochemical and strain-sensing applications have been carried out to detect the physiological signals and parameters of the human body. These prototypes have been classified based on the physical nature of graphene used to formulate the sensors. Finally, the current challenges and future perspectives of these graphene/PDMS-based wearable sensors are explained in the final part of the paper.

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Advanced materials-integrated electrochemical sensors as promising medical diagnostics tools: A review

Cited by 76 publications

References 330 publications

Electrochemical Impedance Spectroscopy in the Characterisation and Application of Modified Electrodes for Electrochemical Sensors and Biosensors

Electrochemical Impedance Spectroscopy in the Characterisation and Application of Modified Electrodes for Electrochemical Sensors and Biosensors

Laser‐induced Graphene in Facts, Numbers, and Notes in View of Electroanalytical Applications: A Review

Integration of Different Graphene Nanostructures with PDMS to Form Wearable Sensors

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