Advanced Nanomaterials in Multimodal Imaging: Design, Functionalization, and Biomedical Applications

Abstract

The biomedical applications of nanoparticles in molecular imaging, drug delivery, and therapy give rise to the term “nanomedicine” and have led to ever-growing developments in the past decades. New generation of imaging probes (or contrast agents) and state of the art of various strategies for efficient multimodal molecular imaging have drawn much attention and led to successful preclinical uses. In this context, we intend to elucidate the fundamentals and review recent advances as well as to provide an outlook perspective in these fields.

<i>In vitro</i> cytotoxicity of biosynthesized titanium dioxide nanoparticles in human prostate cancer cell lines

“…These unique interactions between nanoparticles (NPs) and biomolecules may have applications for cancer diagnosis and treatment [1][2][3][4]. Titanium oxide nanoparticles (TiO 2 NPs) have been used in a wide range of commercial applications, particularly in consumer products such as textiles, laundry additives, room sprays, water purifiers, and food storage containers [5][6][7][8][9][10].…”

Nanotoxicity: Dimensional and Morphological Concerns

“…One is the minimal sample preparation required and the second is its nonselectivity in metabolite detection and ability of multiple metabolite quantification. 1 HNMR provides both quantitative and structural information by enabling to detect soluble proton-containing small-molecular-weight metabolites less than 1000 Da that are present in concentrations above 10 μM. Given the amount and complexity of spectroscopic data from NMR studies, pattern recognition approaches and chemometric analysis were usually used to implement the interpretation of spectral data [166,167].…”

“…Nanoscience and nanotechnology promise for creating new materials with enhanced properties and potential applications [1,2]. The properties of these various types of intentionally produced nanomaterials and nanoparticles enable potential application in commercial, medical, environmental sectors and so forth.…”

Advances in cancer therapy through the use of carbon nanotube-mediated targeted hyperthermia

“…[1][2][3][4][5][6][7][8] Carbon nanotubes (CNTs), with their unique physical and chemical properties, hold great promise for drug delivery and cancer therapy. 9 The research mechanisms of selective tumor targeting with biofunctionalized CNTs are currently being intensely explored due to their impressive ability to convert near-infrared (NIR) laser radiation into heat.…”