“…Endress and Bruyns (2000) recognized five subfamilies: Rauvolfioideae and Apocynoideae from the traditional Apocynaceae, and Periplocoideae, Secamonoideae, and Asclepiadoideae from the traditional Asclepiadaceae. Since then a number of phylogenetic studies have contributed to the resolution of relationships at the tribal, subtribal, or generic level, which has led to the reorganization or description of tribes and subtribes and the synonymization of several genera (e.g., Meve & Liede, 2004;Simões et al, 2004Simões et al, , 2006Simões et al, , 2010Liede-Schumann et al, 2005;Rapini et al, 2006Rapini et al, , 2011Endress & Hansen, 2007;Endress et al, 2007aEndress et al, , 2007bLivshultz et al, 2007;Silva et al, 2012;Khanum et al, 2016;Meve et al, 2017;Morales et al, 2017). Despite these advances, many groups are still unresolved or the resolution is too low to accurately define their relationships.…”