Advances in upper airway cough syndrome

Yu, Li; Xu, Xianghuai; Lv, Hanjing; Qiu, Zhongmin

doi:10.1016/j.kjms.2015.01.005

Cited by 31 publications

(54 citation statements)

References 32 publications

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“…Historically, the diagnosis of UACS has been determined by considering a combination of criteria including symptoms, physical examination and response to therapy with antihistamines. However, all of them are relatively sensitive but non-specific (26). The main clinical characteristics that may help distinguish PBB from rhinosinusitis and adenoiditis are shown in the Table 1.…”

Section: Upper Airway Cough Syndromementioning

confidence: 99%

Wet Cough and Nasal Symptoms in Children: Can We Do Better?

Benedictis

Carloni²,

Comberiati

et al. 2019

Front. Pediatr.

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The causes of chronic cough in children are mainly dependent on the setting and age of the child. Protracted bacterial bronchitis is a frequent cause of morbidity in childhood, and antibiotic treatment is beneficial. Prompt recognition and early treatment is important both to prevent inappropriate use of asthma medications and also progression to bronchiectasis, but the diagnosis should not be made uncritically, because chronic wet cough is not necessarily due to lower airway disease. Upper Airway Cough Syndrome (UACS) is considered by some to cause chronic cough in childhood. Underlying UACS are many common conditions, including allergic rhinitis, adenoiditis and rhinosinusitis. Diagnosis relies on a combination of clinical criteria that are relatively sensitive but non-specific. The role of nasal endoscopy in children with chronic cough and signs suggesting UACS is unclear. Nasal saline solution irrigation is commonly used in UACS, but most studies have methodological biases, and efficacy data are scanty. Randomized controlled trials are urgently required. However, if saline washes, rather than oral antibiotics, can effectively treat some children with wet cough associated with upper airway conditions, antibiotic resistance could potentially be reduced. There is a need to further study wet cough and not to assume it to be equivalent to lower airway infection in all children.

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Section: Upper Airway Cough Syndromementioning

confidence: 99%

Wet Cough and Nasal Symptoms in Children: Can We Do Better?

Benedictis

Carloni²,

Comberiati

et al. 2019

Front. Pediatr.

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show abstract

“…The various proposed pathogeneses of UACS are as follows: the primary theory of postnasal drip then the chronic airway inflammation theory and a recent theory of sensory neural hypersensitivity. In addition, some scholars suggest that UACS is a clinical phenotype of cough hypersensitivity syndrome (6).…”

Section: Contextmentioning

confidence: 99%

“…While the general principles of UACS treatment are similar worldwide, the details of the treatment are different (6). The treatment of PND is often based on the presence of a specific disease.…”

Section: Contextmentioning

confidence: 99%

Relationship Between Cerebrospinal Fluid and Catarrh According to Avicenna

Choopani

Kaveh

Sadr

et al. 2016

Arch Pediatr Infect Dis

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Context: A postnasal drip (PND) or catarrh refers to the drainage of secretions from the paranasal sinuses or nose into the posterior nasal space and the oropharynx. A history of pharyngeal or postnasal mucus build-up may be at odds with the lack of other physical findings and the absence of systematic clinical data. The physiological basis and suitable treatments for PND have been insufficiently recorded in the medical literature. However, Iranian traditional medicine (ITM), which has a history of thousands of years, has discussed in detail the causes, origins, complications, and treatment of catarrh. Communication and cooperation between conventional and traditional medicine can lead to positive steps in solving the ambiguities related to catarrh. The present paper examines the origin of catarrh according to Avicenna and compares it with that described in conventional medicine. Evidence Acquisition: In this study, we examined a major resource of ITM, the Qanoon fi al-teb (The Canon of medicine), by Avicenna and the writings of prominent ancient scholars and physicians on the origins of catarrh. PubMed and Google scholar were also searched for information on PND and catarrh, and they were compared with the catarrh in ITM. Results: Physicians of ITM believe that the main substance in catarrh is discharged from the brain and that it is a connection between the brain and nasopharyngeal space. New scientific findings also confirm the relationship between cerebrospinal fluid (CSF) and catarrh, in common with that described by Avicenna thousands of years ago. Conclusions: Catarrh is a serious condition and requires more investigation. It is hoped that a joint study of conventional and traditional medicine can elucidate different aspects of catarrh.

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“…These conditions can be silent (no symptoms besides cough) in up to 20% of cases. [8] Because of disease chronicity, it is likely that, over time, patients will become tolerant to other symptoms, which are not as bothersome as cough. The diagnosis of silent UACS can reliably be made only after patients show a significant improvement with prescribed treatment directed to suggestive features in history, physical examination, or laboratory testing.…”

mentioning

confidence: 99%

“…Unlike silent UACS, the diagnosis of C-VA can be confirmed in most cases with pre- and post-bronchodilator spirometry with or without methacholine challenge test (MCT). [8]…”

mentioning

confidence: 99%

Management of chronic unexplained cough

Al-Hajjaj

2017

Ann Thorac Med

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Advances in upper airway cough syndrome

Cited by 31 publications

References 32 publications

Wet Cough and Nasal Symptoms in Children: Can We Do Better?

Wet Cough and Nasal Symptoms in Children: Can We Do Better?

Relationship Between Cerebrospinal Fluid and Catarrh According to Avicenna

Management of chronic unexplained cough

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