Aetiology of Lower Respiratory Tract Infection in Benin City, Nigeria

Egbagbe, EE; Mordi, RM

doi:10.4314/jmbr.v5i2.10687

Cited by 31 publications

(65 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A similar study in Nigeria showed LRTIs was 54.80% in male and 67.10% in female [7]. Gender has varied impact on bacterial incidence as some studies show higher infection in females [21] while others show more in males [20]. Higher growth reported among men in our study might be due to lifestyle factors like smoking and alcohol consumption [7].…”

Section: Discussionsupporting

confidence: 53%

“…The frequent incidence of P. aeruginosa in the sputum may be owing to their ability to colonize a wide range of ecological niches, such as air polluting agents, animal hosts and humans [19]. S. pneumoniae was isolated in 6.67% sputum samples in our study, but in most of the other similar world-wide studies, S. pneumoniae has been reported as the chief isolate [7,20,21]. In the present study, the prevalence of K. pneumoniae was 8.67% in the sputum samples.…”

Section: Discussionmentioning

confidence: 42%

See 1 more Smart Citation

Bacterial Etiology of Sputum from Tuberculosis Suspected Patients and Antibiogram of the Isolates

Regmi

Khadka

Adhikari

et al. 2020

Preprint

View full text Add to dashboard Cite

Objective The current study aims to explore the bacteriology of sputum of tuberculosis (TB) suspected patients. A cross-sectional study was carried out in the sputum samples of 150 TB suspected patients visiting District Public Health Office, Bharatpur, Nepal. The samples were subjected to cultural, microscopic and biochemical analyses for the identification of the isolates. In addition, antibiotic susceptibility tests were carried out with a special focus on ESBL and MBL production following Clinical and Laboratory Standard Institute guidelines.ResultsBacterial growth was recovered in 47% (71/150) of the TB suspected patients of which 12.66% (19/150) had pulmonary TB infection. Streptococcus spp. (9%) and Pseudomonas aeruginosa (9%) were the most frequently isolated bacteria. Enterobacteriaceae accounted for 35% of the total isolates. Occurrence of bacterial pathogens was more in males (69%) than in females (31%).The incidence of bacterial pathogen was seen associated with the gender of the patients and with the TB infection (p<0.05) but independent with the age of the patients and HIV infection(p>0.05). Tetracycline was effective against Streptococcus spp. whereas gentamicin was effective against Bacillus spp. Imipenem and co-trimoxazole were effective drugs for Gram-negative isolates. Among 83 isolates, 35 were multi-drug resistant, 9 were ESBL producers and 4 were MBL producers.

show abstract

Section: Discussionsupporting

confidence: 53%

Section: Discussionmentioning

confidence: 42%

Bacterial Etiology of Sputum from Tuberculosis Suspected Patients and Antibiogram of the Isolates

Regmi

Khadka

Adhikari

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

“…The male predominance could be attributed to increasing incidence of smoking and alcohol consumption among males as reported in other studies [21, 22], or probably because females have less access to health care in our country.…”

Section: Discussionsupporting

confidence: 49%

Etiological Trends and Patterns of Antimicrobial Resistance in Respiratory Infections

et al. 2018

View full text Add to dashboard Cite

Background:Respiratory infections are one of the commonest causes of morbidity and mortality related to infectious diseases worldwide. The emergence of antimicrobial resistance is a major global health problem which is well established in developing countries. Good clinical suspicion and correct laboratory identification of respiratory infection causing organisms followed by the appropriate management are needed to compact both community-acquired and nosocomial infection respiratory infections.Objectives:A retrospective study was carried out to elucidate the etiology of respiratory infections in Sudan, as well as to guide the physician to the best antimicrobial alternatives used in the treatment of respiratory infection.Method:Respiratory isolates that have been morphologically identified and biologically characterized were subjected to antibiotic susceptibility testing.Results:A total of 1481 respiratory specimens were examined, recovering 377 organisms from 350 culture positive samples [225(59.7%) sputum, 94(24.9%) broncho-alveolar lavage (BAL), 58(15.4%) Pleural fluid], the commonest organisms were Klebsiella ssp. (25.20%) and mycobacterium tuberculosis (25.20%), followed by Staphylococcus aureus(19.89%) and Pseudomonas aeruginosa(8.49%). High rate of resistance of bacterial isolates was observed to Co-trimoxazole (BA), Ampicillin sulbactam (AS), Cefotaxime (CF) and Tetracycline (TE), being 80%, 72.3%, 68.8% and 66.9% respectively; on the other hand, very low resistance rate was found to Amikacin (AK) and Levofloxacin (LE), being 4.6% and 8.5%, respectively.Conclusion:Guided prescription of antimicrobial agents must be implemented and controlled to limit further spread of antimicrobial resistance.

show abstract

“…Current knowledge of the organisms that cause LRTIs and their antibiotic susceptibility profiles are therefore necessary for the prescription of appropriate therapy [9]. Changes in the characteristics of the population as it ages and the swelling numbers of patients with immunocompromising conditions have increased the number of individuals at risk [2].…”

Section: Introductionmentioning

confidence: 99%

Identification of Bacteria Associated With Lower Respiratory Tract Among Patients Attending in General Hospital Dr. Pirngadi Medan

Naldi

Rosidah

Loesnihari

2018

Asian J Pharm Clin Res

View full text Add to dashboard Cite

Objective: The aim of this study was to establish cases of bacteria associated with lower respiratory tract infections (LRTIs) in General Hospital Dr. Pirngadi Medan with the view to identify the bacteria well as to assess their antibiotics susceptibility.Methods: An observation and prospective study were analyzed to patients with lower respiratory tract infection in respiratory and internal wards Dr. Pirngadi Hospital Medan. For the identification method of bacteria was using optochin test, catalase test, Mannitol salt agar, coagulase, indole, methyl red, Voges–Proskauer test, citrate, urease, and Triple Sugar Iron test.Results: The bacteria that cause lower respiratory tract infection were Pseudomonas aeruginosa (25.53%), Klebsiella pneumoniae (17.02%), Proteus sp. (14.89%), Staphylococcus aureus (12.77%), Escherichia coli (10.64%), Streptococcus pneumoniae (10.64%), and Haemophilus influenzae (8.51%). The result of sensitivity testing showed that gentamicin is more sensitive and the resistant antibiotic is chloramphenicol among all the tested antibiotics.Conclusion: P. aeruginosa was the most common isolated from LRTIs patients with gentamicin is the most sensitive antibiotics while chloramphenicol is the most resistant antibiotics among all the tested antibiotics.

show abstract

Aetiology of Lower Respiratory Tract Infection in Benin City, Nigeria

Cited by 31 publications

References 7 publications

Bacterial Etiology of Sputum from Tuberculosis Suspected Patients and Antibiogram of the Isolates

Bacterial Etiology of Sputum from Tuberculosis Suspected Patients and Antibiogram of the Isolates

Etiological Trends and Patterns of Antimicrobial Resistance in Respiratory Infections

Identification of Bacteria Associated With Lower Respiratory Tract Among Patients Attending in General Hospital Dr. Pirngadi Medan

Contact Info

Product

Resources

About