Age-related fragility fracture: insights from the natural homeostatic system in the skeleton

Sugiyama, Toshihiro; Kono, Y.; Sekiguchi, K.; Kim, Yoon Taek; Oda, Hiromi

doi:10.1007/s11657-015-0251-2

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Mechanical Strain: the Primary Determinant Of Bone Modeling1

обзоры и рецензии1

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Cited by 5 publications

(2 citation statements)

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“…The latter would be normally under the mechanical strain-related feedback control (3–5); Wolff’s law, established more than a century ago, confirms that mechanical environment plays a key role in controlling skeletal architecture (9), and the pattern of trabecular bone in the hip (Singh index) can be used for the evaluation of osteoporosis (10). In addition, this natural homeostatic system could work against mineral-related, but not collagen-related, impairment of bone material quality (11, 12). …”

Section: Mechanical Strain: the Primary Determinant Of Bone Modelingmentioning

confidence: 99%

Osteoporosis Therapy: Bone Modeling during Growth and Aging

Sugiyama

Oda

2017

Front. Endocrinol.

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