Agenesis of second premolars and delayed dental maturation

Gelbrich, Bianca; Hirsch, A.; Dannhauer, Karl-Heinz; Gelbrich, Götz

doi:10.1007/s00056-015-0295-3

Cited by 15 publications

(9 citation statements)

References 15 publications

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“…Among permanent teeth, #35 and #45 are most susceptible to delayed development, and considering the delayed permanent dentition of our patient, observing the formation of her premolars in the near future is not impossible (though it is unlikely). On the other hand, agenesis of second premolars is associated with late maturation of permanent dentition, as is evident in our patient [4,25].…”

Section: Discussionsupporting

confidence: 64%

Dental management of a pediatric patient with progressive familial intrahepatic cholestasis having dental anomalies: a case report and brief review of the literature

et al. 2023

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Background Progressive familial intrahepatic cholestasis is a heterogeneous group of disorders, leading to intrahepatic cholestasis, with the possibility of chronic liver failure and biliary cirrhosis. Oligodontia is either the manifestation of a specific syndrome or is non-syndromic. To the best of our knowledge, this is the first case report of type 3 progressive familial intrahepatic cholestasis and concurrent oligodontia, craniosynostosis, dens in dente, taurodontism, and delayed permanent dentition in the medical and dental literature. Case presentation We present the dental and medical histories and comprehensive dental management of a girl with type 3 progressive familial intrahepatic cholestasis and several dental anomalies, who was referred to a dental clinic due to severe dental caries and pain. Conclusion Our findings suggest that PFIC with manifestations as oligodontia, craniosynostosis, dens in dente, taurodontism, and delayed permanent dentition, might indicate an unknown syndrome; otherwise, the craniofacial anomalies are the manifestations of an independent disease coinciding with PFIC. Moreover, our case is a good example of the importance of timely medical and dental care in confining further health-related complications. The patient was able to ingest without any pain or discomfort after receiving proper dental management.

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Section: Discussionsupporting

confidence: 64%

Dental management of a pediatric patient with progressive familial intrahepatic cholestasis having dental anomalies: a case report and brief review of the literature

et al. 2023

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“…We did not find significant differences in dental development between both groups, although the existence of a greater number of patients with dental agenesis of incisors over premolars (patients with bilateral dental agenesis of premolars had to be excluded) may have biased this analysis. Although most of the studies consulted consider agenesis without differentiating the dental group, Gelbrich et al [36] concludes that the agenesis of the second premolar is not a purely local defect, since its association with the delay in dental maturation raises the suspicion of the existence of a common aetiology.…”

Section: Discussionmentioning

confidence: 99%

Association between dental agenesis and delay in dental development: a preliminary study in a Spanish paediatric population in relation with Dental Anomaly Pattern (DAP)

et al. 2022

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Background The association between dental anomalies has been studied, giving rise to the concept of Dental Anomaly Pattern (DAP). Tooth agenesis has been associated with alterations such as molar infracclusion, taurodontism and delayed dental development. The aim of this study was to evaluate the dental development pattern in patients with non-syndromic dental agenesis, in comparison with a control group. Methods Dental and chronological age was analysed in a sample size of 204 orthopantomographs divided into a study group (n = 104) and a control group (n = 100) with the Demirjian Method. Intra and intergroup differences in chronological and dental age, and the correlation between them were calculated by statistical analysis with a 95% confidence level (p < 0.05). Results Dental age exceeded chronological age both in the control group and in the study group. Statistically significant differences (p = 0.004) were found when comparing the difference between chronological and dental age in the study (-0.16 ± 1.12) and control group (-0.58 ± 0.90). Regarding sex and age intergroup differences, the results were only statistically significant in the girls’ group (p = 0.017), and the age over 8 years old (p < 0.05). There were no significant differences in tooth development depending on the number of missing teeth or the affected tooth group, but there was a delay in the development of the homologous tooth contralateral to the absent one in 14.9% of patients. Conclusions The difference between chronological and dental age in permanent dentition is significantly lower in Spanish children with non-syndromic agenesis compared to a control group, presenting a lower dental age than chronological age than children without non-syndromic agenesis.

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“…In this manner, several attempts to enhance the accuracy of age estimation have been performed, and many pieces of research have been performed considering other factors that may affect dental age estimation techniques, namely socioeconomic status, population affinity, chromosomal anomalies, and diseases, among others [ 7 – 11 ]. The presence of agenesis, i.e., the congenital absence of teeth, has also been referred to as a variable to consider in age estimation [ 12 , 13 ]. Dental agenesis or hypodontia is one of the most common anomalies in the development of human dentition [ 14 ] and is frequently associated with several other oral abnormalities [ 15 – 17 ].…”

Section: Introductionmentioning

confidence: 99%

Does third molar agenesis influence the second lower molar mineralization?

Ferreira,

Caldas

2023

Int J Legal Med

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Different studies have established that the mineralization stages of the second mandibular molar can be used in forensic age estimation. Nowadays, the estimate’s accuracy is an ethical concern, producing as few false positives (individuals incorrectly classified as older than a determined threshold) and false negatives (individuals incorrectly classified as younger than a determined threshold) as possible. Some have hypothesized that changes in teeth number may influence tooth mineralization, altering the age estimate process. This paper analyzes whether third molar agenesis affects the second mandibular molar mineralization time frame. To do so, 355 orthopantomograms were evaluated for third molar agenesis, and the second mandibular molar mineralization stage was assessed using the Demirjian stages. Student’s t-test was used to compare the difference in the mean age at which the various stages of 37 mineralization were reached in the groups with and without third molar agenesis. The level of statistical significance was set at 5%. The results pointed to a delay in second mandibular molar mineralization in the case of agenesis, suggesting the need to consider this when estimating age using dental techniques.

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Agenesis of second premolars and delayed dental maturation

Cited by 15 publications

References 15 publications

Dental management of a pediatric patient with progressive familial intrahepatic cholestasis having dental anomalies: a case report and brief review of the literature

Dental management of a pediatric patient with progressive familial intrahepatic cholestasis having dental anomalies: a case report and brief review of the literature

Association between dental agenesis and delay in dental development: a preliminary study in a Spanish paediatric population in relation with Dental Anomaly Pattern (DAP)

Does third molar agenesis influence the second lower molar mineralization?

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