Aggressive angiomyxoma presenting as polyp of uterine cavity

Aggressive Angiomyxoma of the Cervix: A Unique Entity

“…Patients are often asymptomatic and compression to urinary/intestinal systems occurs only when the tumour is large. Very rarely, and to our knowledge, only two cases have been reported where it has presented as a cervical polyp with symptoms of distension or a uterine polyp where it presented with uterine bleeding and urinary retention [5,6]. Aggressive angiomyxoma is thought to be estrogen and progesterone sensitive and presents usually in the reproductive age group, with some cases reporting growth of the tumour during pregnancy [2,7].…”

A solitary encapsulated pelvic aggressive angiomyxoma

“…[1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20] Its radiological features have been described, being a displacing mass rather than infiltrating, with high signal intensity on T2-weighted images, 1,14,15 but these features can be attributed to the myxoid component of the tumour, shown by many other soft tissue tumours of mesenchymal origin. On gross examination, it was different in being well circumscribed non-lobulated and encapsulated, [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20] but the gelatinous appearance, greyish discoloration on cross section and the large size of the tumour are common features of AAMs. These findings are attributed to the myxoid stroma that is rich in collagen fibres.…”

“…In addition, sporadic reports of recurrences in sites different than the originally excised mass, and the reports of unusual locations or presentations of this tumour, e.g. multifocal AAM, 20 the bladder, 12 and the uterine cavity 13 (e.g. polypoidal mass in the last two sites, occasionally), etc., are all in favour of an isolated primitive mesenchymal cell origin.…”

“…4,18 Complete excision is the treatment of choice. [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20] We believe that 1-2 yearly intervals of follow-up with alternate MRI and sonography is sufficient in view of the slow growing and nonmetastasising nature of this tumour.…”

“…6,7 We have found reports of involvement of every pelvic organ, including the urinary bladder 12 and uterus. 13 The true origin of this tumour is unknown, but few articles have raised the possibility of an isolated mesenchymal cell origin.…”