AKTIVITAS SITOTOKSIK SENYAWA METABOLIT SEKUNDER KAPANG ENDOFIT Evodia suaveolens DENGAN METODE BSLT (Brine Shrimp Lethality Test)

Abstract

Abstrak Kanker adalah penyakit degeneratif dengan kasus yang makin meningkat setiap tahunnya. Menurut WHO (World Health Organization) (2003) kasus kanker dunia diprediksi akan mengalami peningkatan 50% menjadi 15 juta kasus pada tahun PENDAHULUAN Kanker merupakan penyakit degeneratif yang mematikan. Menurut WHO (World Health Organization) (2003) kasus kanker dunia diprediksi akan mengalami peningkatan 50% menjadi 15 juta kasus pada tahun 2020. Sebagian besar penyakit kanker disebabkan oleh lingkungan dan gaya hidup. Faktor

ANTIOXIDANT, TOXICITY AND ANTIBACTERIAL PROPERTIES OF Ompu-ompu (Crinum asiaticum-L) ETHANOL EXTRACT

“…It is presumed that the "Ompu-ompu"is considered as a potential and promising medicinal plant. Because the plants have toxic properties 18,23 which are similar to the toxicity of the 7 alkaloids found in Licorisaurea(Amaryllidaceae) that have a significant antibacterial activity and even potentially as an anticancer 20 .…”

“…The other important point of concerns in utilizing the plant which is toxic properties. The toxicity of a plant is considered as an indication of the potential of compounds as a medicinal plant (bioactivity) 19,20 . There are 7 types of alkaloids from cognates with Crinum that have significant toxicity and activity against antibacterial and cancer resistance 21 which were tested by the Brine Shrimp Lethality Test (BSLT) 22 .…”