The article considers the current state and the main promising areas of scientific and practi-cal developments in the field of radio electronics. For the space application of mechatronic systems, the microcircuits are characterized by multi-nomenclature low-volume indicators. To create a high-ly reliable electronic component base, it is necessary to ensure resistance to the fields of ionizing radiation from space, a wide range of temperatures and mechanical stresses. This requires the crea-tion of ECBs for space applications that are resistant to these external influencing factors.