Alkaloids from cultivated plant of Peganum harmala L.

Abstract

Alkaloids such as 1H-cyclopenta(b) quinoline, 2.3.5.6.7.8-hexahydro-9-amino-; Vasicinone(1H-Pyrrоlo[2.1-b]quinazolin-9-one,3-hydroxy-2.3-dihydro) and harmine were isolated from cultivated plant of P. harmala. Four unknown alkaloids were isolated from P. harmala for the first time: 2.2.6.6-Tetramethyl-4-piperidone., Quinoline, 2.3.4-trimethyl-., Pyridine, 2-phenoxy-4-amino-and 4-(3-Propynyloxy)-quinazoline. Their structures were determined by GC-MS.

Improving health benefits with considering traditional and modern health benefits of Peganum harmala

“…Asgarpanah and Ramezanloo [26] and Fatma et al [27] announced that the major alkaloids detected and quantified from the intensity of the fluorescence of P. harmala were harmine, harmaline, harmalol and harmol. Javzan et al [28] determined alkaloids such as 1H-cyclopenta(b)quinoline, 2.3.5.6.7.8-hexahydro-9-amino-; Vasicinone (1H-Pyrrolo[2.1-b]quinazolin-9-one,3-hydroxy-2.3-dihydro) and harmine were isolated from cultivated plant of P. harmala. Farouk et al [29] and Khan et al [30] detected alkaloids, saponins, tannins, anthraquinones, flavonoids, flavones, terpenoids, phlobatannins, chalcones and cardiac glycosides in P. harmala Chemical structures of harmala alkaloids are shown in Fig.…”

Alkaloids from Mongolian species of Peganum multisectum (Maxim) Bobrov

“…Amongst them, 9-amino-2,3,5,6,7,8-hexahydro-1Hcyclopenta[b]quinolone 2 (11.501%) was identified as the major alkaloid in the alkaloid extract, while compounds 1 (0.791%), 3 (4.785%) and 4 (0.909%) were detected as the minor (Figure 1 and Table 1) by GC-MS. The structures of the alkaloids were determined based on a comparison of their retention time and mass spectral fragmentation (NIST) with those of reference data in the literature [10]. The other five alkaloids were isolated from the aerial parts of P.multisectum by CC.…”