Amniotic Membrane in the Treatment of Spinal Cord Injuries

Arisawa, Emília Ângela Lo Schiavo

doi:10.26717/bjstr.2017.01.000475

Cited by 1 publication

(1 citation statement)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…They offer several advantages such as minimal invasive isolation and no ethical issues. They also show multipotency, efficient proliferative activity, non-tumorigenicity, and low immunogenicity [17]. The final, adipose tissue (A)-MSCs can be obtained from adipose tissue in large amounts and are characterized by the secretion of trophic growth factors (BDNF and GDNF), modulation of activated immune cells, neuroregeneration, anti-apoptotic action, and multilineage differentiation capacity which may confer potential regenerative effects in SCI [18].…”

Section: Bone Marrow Stem Cells (Bm-mscs)mentioning

confidence: 99%

Trends of Chitosan Based Delivery Systems in Neuroregeneration and Functional Recovery in Spinal Cord Injuries

et al. 2021

View full text Add to dashboard Cite

Spinal cord injury (SCI) is one of the most complicated nervous system injuries with challenging treatment and recovery. Regenerative biomaterials such as chitosan are being reported for their wide use in filling the cavities, deliver curative drugs, and also provide adsorption sites for transplanted stem cells. Biomaterial scaffolds utilizing chitosan have shown certain therapeutic effects on spinal cord injury repair with some limitations. Chitosan-based delivery in stem cell transplantation is another strategy that has shown decent success. Stem cells can be directed to differentiate into neurons or glia in vitro. Stem cell-based therapy, biopolymer chitosan delivery strategies, and scaffold-based therapeutic strategies have been advancing as a combinatorial approach for spinal cord injury repair. In this review, we summarize the recent progress in the treatment strategies of SCI due to the use of bioactivity of chitosan-based drug delivery systems. An emphasis on the role of chitosan in neural regeneration has also been highlighted.

show abstract

Section: Bone Marrow Stem Cells (Bm-mscs)mentioning

confidence: 99%