Amoebic cervicitis mimicking posterior wall fibroid: A rare presentation

Abstract

Amoebiasis of the uterine cervix is an extremely rare entity, and presentation as fibroid uterus has not been reported, to the best of our knowledge in our extensive search of the English literature. It can clinically simulate cervical malignancy by virtue of surface papillomatous and overall ulcerated and necrotic appearance. We present a case of amoebic infection of the cervix in a 45-year-old female which was suspected to be a posterior wall fibroid with degeneration until a histopathological examination of the surgical specimen revealed the presence of Entamoeba histolytica trophozoites. The patient recovered after surgery and antiamoebic therapy.

Tuberculous cervicitis: A brief report with cytohistological correlation and differential diagnosis

“…Other granulomatous diseases of the cervix should be considered, such as amoebiasis, 27 schistosomiasis, 28 sarcoidosis, 29 and history of prior biopsy and surgery 30 should be considered in differential diagnosis.…”

Liquid‐based cytology of amoebic cervicitis clinically mimicking cervical cancer

“…Genital amebiasis is uncommonly reported as the vagina has a highly acidic environment and the squamous epithelium acts as natural barrier for this infection. Metronidazole is commonly used for treatment of bacterial vaginosis, leading to inadvertently treatment of the under recognized infection 5 . The trophozoites of amoeba vary in size from 15 to 20 μm, have peripheral finely granular nuclear chromatin and a small central distinct dot like karyosome 6 .…”

“…Since the amebic ulcers are deep and penetrating, cervical lesions can often mimic large carcinomatous ulcers, raising diagnostic difficulties clinically. It has also been postulated, that the necrotic tissue in cervical/vaginal tumor patients likely provides a niche for trophozoite colonization 5 . Several case reports have been published highlighting a chance diagnosis of cervical amebiasis in an otherwise clinically suspected case of carcinoma cervix 2,4 .…”