Liquid‐based cytology of amoebic cervicitis clinically mimicking cervical cancer

Agarwal, Poojan; Bakshi, Pooja; Verma, Kusum

doi:10.1002/dc.24628

Cited by 2 publications

(2 citation statements)

References 8 publications

(13 reference statements)

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“…ICC is not only a clinical manifestation of high-risk CIN but also an early pathological manifestation of cervical cancer. Because the process of differentiation and expression of cancer cells are very disorderly, the abnormal expression of vascular endothelial genes can lead to invasive invasion of cancer cells and diversified expression of cancer markers, which will cause certain difficulties in direct vision and pathological film reading [17][18][19]. Many studies have shown that the diagnostic rate of ICC colposcopic cervical biopsy remains to be improved, and its detection rate is affected by many factors, such as the number of lesion-involved points [20,21].…”

Section: Discussionmentioning

confidence: 99%

Diagnosis of Cervical Intraepithelial Neoplasia and Invasive Cervical Carcinoma by Cervical Biopsy under Colposcopy and Analysis of Factors Influencing

Wang

Mei

2022

Emergency Medicine International

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Objective. To explore the diagnosis of cervical intraepithelial neoplasia (CIN) and invasive cervical carcinoma (ICC) by cervical biopsy under colposcopy and analyze the factors influencing the detection. Methods. The clinical data of 134 CIN confirmed by colposcopy biopsy in our hospital from June 2018 to October 2019 and subsequent LEEP treatment were analyzed retrospectively. All patients were diagnosed pathologically after the operation. The diagnosis of CIN by cervical biopsy under colposcopy was observed. The influencing factors of CIN and ICC detected by colposcopy biopsy were analyzed by the pathological results of loop electrosurgical excision procedure (LEEP) as the gold standard. Results. After LEEP, the number of the no intraepithelial or malignant lesions (NILM) or ICC were higher than that of colposcopy biopsy, and CIN-III was lower than that of colposcopy biopsy, the differences were all statistically significant ( P < 0.05 ). Among the 134 patients, the coincidence rate between colposcopy biopsy and LEEP examination results was 79.10% (106/134), and postoperative pathological findings showed that there were 13 cases (9.70%) with the pathological upgrade and 19 cases (14.18%) with pathological decrease. Multivariate logistic analysis showed that the image quality of colposcopy image, atypical blood vessels, biopsy sampling method, and visible lesion area of the cervix were the independent influencing factors for the detection of CIN and ICC by colposcopy biopsy ( P < 0.05 ). Conclusion. CIN and ICC can be diagnosed by colposcopy cervical biopsy and postoperative histopathology. However, there are still some missed and misdiagnosed cervical biopsies under colposcopy, and the combined detection of the two can further ensure the diagnosis rate. The clinical registration number is E2018091.

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Section: Discussionmentioning

confidence: 99%

Diagnosis of Cervical Intraepithelial Neoplasia and Invasive Cervical Carcinoma by Cervical Biopsy under Colposcopy and Analysis of Factors Influencing

Wang

Mei

2022

Emergency Medicine International

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“…Some patients with chronic cervicitis show no obvious clinical symptoms. Symptomatic patients usually have persistent or recurrent increased leucorrhea, which is often milky white or pale yellow in color, and the leucorrhea is viscous and purulent, sometimes with blood streaks (6,7). It can also be manifested as frequent pain in the lower abdomen or lumbosacral region, as well as some bladder and bowel symptoms.…”

Section: Introductionmentioning

confidence: 99%

Loop Electrosurgical Excision Procedure under Propofol Intravenous Anesthesia Combined with Nano-Silver Gel in the Treatment of Cervicitis

Liu¹,

Zou²,

Sun³

et al. 2022

Cell Mol Biol (Noisy-le-grand)

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It was aimed at the therapeutic value of loop electrosurgical excision procedure (LEEP) under propofol intravenous anesthesia combined with nano-silver gel in chronic cervicitis. 100 patients with chronic cervicitis were selected and randomly divided into the control group with 50 cases (LEEP under intravenous anesthesia with fentanyl) and the experimental group with the other 50 cases (LEEP under propofol intravenous anesthesia combined with the nano-silver gel). It was suggested from the results that the mean arterial pressure (MAP) and heart rate (HR) (76.88±5.65mmHg, 75.45±5.06beats/min) of patients in the experimental group at T1 time were better than those of the control group (83.76±5.43mmHg, 68.31±5.28beats/min). Visual analogue scale (VAS) (1.85±0.73 points), onset time of anesthesia (0.56±0.21min), time to open eyes (2.45±1.38min) and time of consciousness recovery (5.22±1.42min) were all lower than those of the control group (2.83±0.79 points, 0.93±0.25min, 4.33±1.45min, and 7.15±1.34min, respectively). The incidence of adverse reactions, the effective rate of treatment, the time of wound healing, and the incidence of complications (6%, 94%, 23.83±2.05 days, and 6%, respectively) were all better than those of the control group (24%, 70%, 29.25±2.16 days, and 6%) (P<0.05). All in all, intravenous anesthesia with propofol was beneficial to perform LEEP better, and the combination of LEEP combined with nano-silver gel had an important value in the treatment of chronic cervicitis and was worthy of clinical promotion.

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Liquid‐based cytology of amoebic cervicitis clinically mimicking cervical cancer

Cited by 2 publications

References 8 publications

Diagnosis of Cervical Intraepithelial Neoplasia and Invasive Cervical Carcinoma by Cervical Biopsy under Colposcopy and Analysis of Factors Influencing

Diagnosis of Cervical Intraepithelial Neoplasia and Invasive Cervical Carcinoma by Cervical Biopsy under Colposcopy and Analysis of Factors Influencing

Loop Electrosurgical Excision Procedure under Propofol Intravenous Anesthesia Combined with Nano-Silver Gel in the Treatment of Cervicitis

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