An Air-Driven Fluidic Multiplexer Integrated with Microdispensers

Puntambekar, Aniruddha; Choi, Jin‐Woo; Ahn, Chong H.; Kim, Sura; Bayyuk, Sami; Makhijani, Vinod B.

doi:10.1007/978-94-010-1015-3_27

Cited by 6 publications

(1 citation statement)

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“…We have previously reported the development of a smart, passive microfluidic control technique, which relies on the geometrical dimensions and surface properties of the microfluidic channels to control microfluidic sequencing. 17,18 It is highly required for microfluidic sealing to prevent blood sample backflow when delivering blood sample to the sensing chamber by applying pressure.…”

Section: Methodsmentioning

confidence: 99%

Development of functional lab-on-a-chip on polymer for point-of-care testing of metabolic parameters

Lee

Han

et al. 2008

Lab Chip

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This paper presents the development of an easy-to-handle and disposable clinical diagnostic lab-on-a-chip using fully integrated plastic microfluidic components, which has the sampling/identifying capability to make fast and reliable measurements of metabolic parameters from human whole blood. A smart and functional lab-on-a-chip cartridge, which incorporates a full on-chip auto-calibration function for in the field applications, has been developed, and then fully characterized using a portable analyzer (3 (1/4)''x 5''x 1'') with multi-analyte detection capability. In addition, several new approaches in realizing smart and functional lab-on-a-chips on polymer have been adopted, which include the pinch valve for automatic fluidic sealing, a by-pass channel as the sampling indicator, and a robust connector design for long analyzer lifetimes. Metabolic parameters such as glucose, lactate, and partial oxygen from human whole blood have been successfully measured using the functional polymer lab-on-a-chips and the portable analyzer developed in this work.

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Section: Methodsmentioning

confidence: 99%