“…Nahor et al (2003) minimised the ratio of the largest to the smaller eigenvalue of the FIM to compute optimal temperature sensor positions for food processes. To the best of our knowledge, these techniques have not been applied yet to systems described by partial differential equations, in spite of their resolute advantages (Uciński, 1999, Löhner and Camelli, 2005, Waterhouse et al, 2009, Vande, 2000, Venkateswarlu and Kumar, 2006, Punithakumar et al, 2006, Peng, 2005, Cotae et al, 2008, Balsa-Canto et al, 2008. Christofides and Antoniades (2000, 2001 presented new approaches to calculate the optimal actuator/sensor locations of uncertain transportreaction systems under control.…”