An Assessment of the Accuracy of Hepatic and Splenic Size Based Upon a Clinician’s Physical Examination, a Radiologist’s Impression and the Actual Liver and Spleen Volumes Calculated by CT Scanning

Sajjad, Shabbar; García, Moisés Salamanca; Malik, Ahmed Hassaan; Thiel, David H. Van

doi:10.1007/s10620-007-0087-8

Cited by 5 publications

(4 citation statements)

References 24 publications

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“…Triple-phase abdominal computed tomography scan was performed to evaluate of the hepatic morphology, hepatic vessels (arteries and veins), multiple portosystemic shunts especially esophageal varices, and to determine the liver volume (LV) and spleen volume (SV) [17]. Gastroscopy (by PENTAX EPM-3500, PENTAX Inc., Tokyo, Japan) was performed to determine whether varices existed in the lower part of esophagus and the stomach.…”

Section: The Abdomen Ct and Gastroscopymentioning

confidence: 99%

A Novel Canine Model of Portal Vein Stenosis Plus Thioacetamide Administration-Induced Cirrhotic Portal Hypertension With Hypersplenism

Lin

et al. 2011

Cell Biochem Biophys

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Current large animal models that could closely resemble the typical features of cirrhotic portal hypertension in human have not been well established. Thus, we aimed to develop and describe a reliable and reproducible canine cirrhosis model of portal hypertension. A total of 30 mongrel dogs were randomly divided into four groups: 1 (control; n = 5), 2 (portal vein stenosis [PVS]; n = 5], 3 (thioacetamide [TAA]; n = 5), and 4 (PVS plus TAA; n = 15). After 4-months modeling period, liver and spleen CT perfusion, abdominal CT scans, portal hemodynamics, gastroscopy, hepatic function, blood routine, the bone marrow, liver, and spleen histology were studied. The animals in group 2 (PVS) developed extrahepatic portosystemic collateral circulation, particularly esophageal varices, without hepatic cirrhosis and portal hypertension. Animals from group 3 (TAA) presented mild cirrhosis and portal hypertension without significant symptoms of esophageal varices and hypersplenism. In contrast, animals from group 4 (PVS + TAA) showed well-developed micronodular and macronodular cirrhosis, associated with significant portal hypertension and hypersplenism. The combination of PVS and TAA represents a novel, reliable, and reproducible canine cirrhosis model of portal hypertension, which is associated with the typical characteristics of portal hypertension, including hypersplenism.

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Section: The Abdomen Ct and Gastroscopymentioning

confidence: 99%

A Novel Canine Model of Portal Vein Stenosis Plus Thioacetamide Administration-Induced Cirrhotic Portal Hypertension With Hypersplenism

Lin

et al. 2011

Cell Biochem Biophys

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“…A variety of bias determines and/or affects the radiologist's assessment of liver size but not of splenic size. 5 Assessment of splenic size, based on subjective parameters or a longitudinal length by ultrasonogram alone, but spleen is an irregularly shaped three dimensional organ that may enlarge at different rates in its various dimensions (length, width and thickness). So, physical examination and imaging using one-dimensional measurement may underestimate the organ size.…”

Section: Introductionmentioning

confidence: 99%

Splenic Volume: Correlation between Ultrasonogram and Standard CT Measurements

Paul¹,

Taher

Jahan³

et al. 2018

Bangladesh Med Res Counc Bull

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Evaluation of splenic enlargement is important in the diagnosis and management of various diseases including liver disease, lymphoma and other primary or metastatic neoplasm. This cross sectional study was conducted in the Department of Radiology and Imaging in Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM) from July 2007 to June 2009. The main objective of the study was to find out a more accurate sonographic measurement of splenic volume that well correlate with gold standard computed tomography (CT) volume. A total of 228 subjects were included in the study. All the subjects underwent ultrasound and CT examinations for measurement of splenic volume. 3 . Sonographic splenic volumes were calculated by using the prolate Ellipsoid method AVL (average length) and also expressed in cm 3 .The mean difference of splenic volume evaluated by CT and sonography was 7.43±5.39 cm 3 with standard deviation of 5.39 cm 3 measured from average length (AVL). The mean difference of splenic volume evaluated by two modalities measured by average length was statistically significant (p<0.05).A significant positive correlation was found between splenic volume evaluated by CT and ultrasonogram by using the Prolate Ellipsoid method AVL (r=0.9854, p<0.001).

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“…In this regard, hepatic volume measurement provides useful and even critical information in a large range of clinical situations. It is mandatory before living donor liver transplantation [4], before extensive partial resection to estimate the volume of the remaining liver [5] and in patients with diffuse liver disease to monitor response to therapy [6,7]. Hepatic volume measurement has also proven utility for determining prognosis in patients with fulminant hepatic failure [8].…”

Section: Introductionmentioning

confidence: 99%

“…However, this approach provides an unreliable prediction of the actual liver volume [7]. By contrast, calculation of hepatic volume from CT data using dedicated software provides an accurate measurement of liver volume [5,9,10].…”

Section: Introductionmentioning

confidence: 99%

Hepatic Height on Coronal Computed Tomography Images Predicts Total Liver Volume in European Adults Without Liver Disease

et al. 2012

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An Assessment of the Accuracy of Hepatic and Splenic Size Based Upon a Clinician’s Physical Examination, a Radiologist’s Impression and the Actual Liver and Spleen Volumes Calculated by CT Scanning

Abstract: A variety of biases determine and/or affect the radiologist's assessment of liver size but not of splenic size.

Cited by 5 publications

References 24 publications

A Novel Canine Model of Portal Vein Stenosis Plus Thioacetamide Administration-Induced Cirrhotic Portal Hypertension With Hypersplenism

A Novel Canine Model of Portal Vein Stenosis Plus Thioacetamide Administration-Induced Cirrhotic Portal Hypertension With Hypersplenism

Splenic Volume: Correlation between Ultrasonogram and Standard CT Measurements

Hepatic Height on Coronal Computed Tomography Images Predicts Total Liver Volume in European Adults Without Liver Disease

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