The use of interlocking toy building blocks (e.g., LEGO) as teaching modules with a focus on the topics in organic chemistry is presented. Interlocking building blocks were assembled on a baseplate to depict chemistry concepts of hydrogenation of alkenes, hydration of alkenes, Markovnikov's rule, cis and trans isomers, hydrogen bonding, optical isomers, esterification, and amidation. The modules were presented to illustrate these topics in an undergraduate chemistry course for allied health majors. Modules were presented on a document camera for in-person and online modes of delivery. A quiz was implemented to assess the efficacy of the modules. Preliminary evaluation results underlined the efficacy of the interlocking toy modules for delivering concepts in organic chemistry.