An efficient one-pot synthesis of highly substituted [1,8]naphthyridin-1-phenyl-1-ethanone derivatives via a four-component reaction

An Efficient Ultrasound Promoted Three‐Component and Regioselective Synthesis of Indenoquinoxaline Compounds Containing Pyrrolopyrimidine Skeleton

“…28 Then, the NH of ketene aminal attacks to the C=O group to form the final product. Based on literature reports, 27,28…”

“…In continuation of our interest in the development of new synthetic procedures in heterocyclic chemistry,, we wish to describe a one‐pot, multi‐component, metal‐free, and regioselective synthesis of novel indeno[1,2‐ b ]quinoxaline compounds containing pyrrolopyrimidine skeleton via sequential ultrasound‐assisted reaction in CH 3 CN in good to excellent yields.…”

“…Therefore, many reactions have been performed using this active site including synthesis of pyrrole-quinoxaline derivatives, [25a] synthesis of functionalized spirolactone-quinoxaline derivatives, [25b] synthesis of spiropyrrolidine-quinoxaline derivatives, [25c] and synthesis of spirobenzo[b]furo[3,4-e][1,4]diazepine-quinoxaline derivatives. [25d] In continuation of our interest in the development of new synthetic procedures in heterocyclic chemistry, [26,27] we wish to describe a one-pot, multi-component, metal-free, and regioselective synthesis of novel indeno[1,2-b]quinoxaline compounds containing pyrrolopyrimidine skeleton via sequential ultrasound-assisted reaction in CH 3 CN in good to excellent yields.…”

A Highly Efficient Synthesis of Pyrrolo[1,2‐a]pyrimidine Derivatives Containing 1,3‐Indandione Skeleton

“…Most of these methods have disadvantages such as high temperatures, metal catalysts, acidic and basic media, difficult process of catalyst preparation, harsh conditions, and etc. Thus, according to our previous studies on the synthesis of fused nitrogen heterocyclic compounds via ketene aminals or enaminones, we have presented a useful method for the preparation of pyrrolo[1,2‐ a ]pyrimidines via a one‐pot three‐component reaction of triethylammonium thiolates 1 , methyl iodide and ketene aminals 3 in DMF at room temperature (Scheme ).…”

An Efficient Regioselective Access to (11Z)‐11‐(3‐Aryl‐5,6‐dihydropyrazin‐2(1H)‐ylidene)‐11H‐indeno[1,2‐b]quinoxaline Derivatives via One‐Pot Three‐Component Reaction

“…The varied class of nitrogen‐containing heterocycles includes a broad fraction of organic products, many of which have found significant applications in agrochemistry, material science, and medicinal chemistry . Thus, there is continuing attention in the expansion of an expeditious, atom‐economic, and environmentally benign synthetic procedures for the preparation of N ‐heterocyclic compounds …”