An electrochemical sensor for l-dopa based on oxovanadium-salen thin film electrode applied flow injection system

Teixeira, Marcos F.S.; Marcolino‐Júnior, Luiz H.; Fatibello‐Filho, Orlando; Dockal, Edward R.; Bergamini, Márcio F.

doi:10.1016/j.snb.2006.06.032

Cited by 91 publications

(36 citation statements)

References 29 publications

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“…Several methods for the determination of LD have been described in literature including high performance liquid chromatography (HPLC) [13], flow injection system [14] and capillary zone electrophoresis [15,16]. Beside the fact that the methods based on electrochemical sensors have many advantages over the other methods, there are few papers on the determination of LD in pharmaceutical formulations using the modified electrodes [17][18][19][20].…”

Section: Introductionmentioning

confidence: 99%

Application of a Carbon‐Paste Electrode Modified with 2,7‐Bis(ferrocenyl ethyl)fluoren‐9‐one and Carbon Nanotubes for Voltammetric Determination of Levodopa in the Presence of Uric Acid and Folic Acid

2011

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A carbon-paste electrode modified with 2,7-bis(ferrocenyl ethyl)fluoren-9-one and carbon nanotubes was used for the sensitive voltammetric determination of levodopa (LD). The electrochemical response characteristics of the modified electrode toward LD, uric acid (UA) and folic acid (FA) were investigated. The results showed an efficient catalytic activity of the electrode for the electrooxidation of LD, which leads to lowering its overpotential by more than 320 mV. The modified electrode exhibits an efficient electron mediating behavior together with well-separated oxidation peaks for LD, UA and FA. Also, the modified electrode was used for determination of LD in some real samples.

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Section: Introductionmentioning

confidence: 99%

Application of a Carbon‐Paste Electrode Modified with 2,7‐Bis(ferrocenyl ethyl)fluoren‐9‐one and Carbon Nanotubes for Voltammetric Determination of Levodopa in the Presence of Uric Acid and Folic Acid

2011

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“…Characteristics of the developed methodology are comparable or better than those proposed in the literature. 12 The advantages of the developed method lie in the use of a solid electrode without any modification, wide dynamic range and possible application in complexes matrices such as extracts from plants containing L-DOPA.…”

Section: Calibration Curvementioning

confidence: 99%

“…[6][7] Based on these facts, different analytical methods, usually based on chromatographic techniques and spectrophotometry, are employed for the quantification of this compound. [8][9][10][11][12][13][14][15][16][17] They possess satisfactory sensitivity and selectivity but the disadvantage of these methods lies in expensive instrumentation and time consuming sample preparation. Also, electroanalytical methods have been presented for the quantification of levodopa.…”

Section: Introductionmentioning

confidence: 99%

Rapid electrochemical method for the determination of L-DOPA in extract from the seeds of Mucuna prurita

Stanković

Samphao²,

Dojčinović³

et al. 2016

ACSi

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This work presents the electrochemical behavior of levodopa (L-DOPA), at boron-doped diamond (BDD) electrodes, using cycling voltammetry (CV), in Britton-Robinson (BR) buffer solution, and application of the proposed electrode for the determination of L-DOPA in extracts from the seeds of velvet bean (Mucuna prurita Hook or Mucuna pruriens (L.) DC.). L-DOPA provides a well-defined and single oval-shape oxidation peak at +0.8 V vs. Ag/AgCl (3 M KCl) reference electrode in BR buffer solution at pH 3.0. Experimental parameters, such as pH of supporting electrolyte and square wave voltammetry (SWV) operating parameters (frequency and modulation amplitude) were optimized. The effect of possible interferences was evaluated. Under optimal conditions the detection limit of the developed method was 0.8 μM and the calibration curve for L-DOPA was linear in the range from 2 to 100 μM. The proposed method was successfully applied to the determination of L-DOPA in an extract from the seeds of Mucuna prurita. The obtained result was in good agreement with obtained by photometry with 2,2´-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid (ABTS). The developed approach can be beneficial for the quantification of L-DOPA using a BDD electrode as up-todate potential alternative sensor for electroanalytical applications.

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“…Alternatively, conducting polymers or self-assembled monolayers can also be used for the electrocatalytic reactions [19,20]. Success of such modified electrodes mainly depends on diffusion of the target analyte through the chemical film to the electrode or to the immobilized electrocatalyst where an electron transfer reaction can occur [21][22][23][24][25]. In the present work, VO 2+ -S is synthesized, characterized, and immobilized on a glassy carbon electrode for the electrocatalytic oxidation and subsequent determination of cysteine.…”

Section: Introductionmentioning

confidence: 99%

Electrocatalytic Oxidation and Determination of Cysteine at Oxovanadium(IV) Salen Coated Electrodes

Sonkar

Ganesan

Rao

2014

International Journal of Electrochemistry

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A transition metal complex, oxovanadium(IV) salen (where salen represents N,N -bis(salicylidene)ethylenediamine) is immobilized on glassy carbon (GC) electrodes and utilized for electrocatalytic oxidation of cysteine. In presence of oxovanadium(IV) salen, increased oxidation current is observed due to the effective oxidation of cysteine by the electrogenerated oxovanadium(V) salen species. The oxidation current linearly varies with the concentration of cysteine from 0.1 to 1.0 mM. The modified electrode has good sensitivity and low limit of detection. These properties make the oxovanadium(IV) salen as an effective electrocatalyst for the determination of cysteine.

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An electrochemical sensor for l-dopa based on oxovanadium-salen thin film electrode applied flow injection system

Cited by 91 publications

References 29 publications

Application of a Carbon‐Paste Electrode Modified with 2,7‐Bis(ferrocenyl ethyl)fluoren‐9‐one and Carbon Nanotubes for Voltammetric Determination of Levodopa in the Presence of Uric Acid and Folic Acid

Application of a Carbon‐Paste Electrode Modified with 2,7‐Bis(ferrocenyl ethyl)fluoren‐9‐one and Carbon Nanotubes for Voltammetric Determination of Levodopa in the Presence of Uric Acid and Folic Acid

Rapid electrochemical method for the determination of L-DOPA in extract from the seeds of Mucuna prurita

Electrocatalytic Oxidation and Determination of Cysteine at Oxovanadium(IV) Salen Coated Electrodes

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