An experimental NMR and computational study of 4-quinolones and related compounds

An experimental and theoretical NMR study of NH-benzimidazoles in solution and in the solid state: proton transfer and tautomerism

“…These equations give excellent results except for atoms (generally, carbon) linked to halogen atoms (I > Br > Cl >> F) [ 11 , 14 ] where relativistic corrections are necessary [ 15 ].…”

Solvent-dependent regio- and stereo-selective reactions of 3-formylchromones with 2-aminobenzothiazoles and transacetalization efficiency of the product 3-((benzo[d]thiazol-2-ylimino)butyl)-4H-chromen-4-one

“…The experiments were performed following the existing literature. 24 BoC protections were performed using the general Synthesis of 4-chloroquinoline-3-carbaldehyde (Q1) and 1,4dihydro-4-oxoquinoline-3-carbaldehyde (Q2). To 50 mL of dry DMF, POCl 3 (23 mL, 246.8 mmol, 6 eq.)…”

Synthesis of (2-Aminophenyl)(naphthalen-2-yl)methanones via Intramolecular Rearrangement of (E)-3-Styrylquinolin-4(1H)-ones under Irradiation with 365 nm UV Light

“…The silica gel (size 200-300 mesh) was used for the column chromatography. 1 H NMR yields shown were determined with 1,3,5-trimethoxybenzene as internal standard. 1 H NMR and 13 C NMR spectra were recorded on Bruker 400 or 600 MHz Spectrometer ( 1 H: 400 MHz or 600 MHz, 13 C: 101 MHz or 151 MHz) using CDCl 3 , DMSO-d 6 or CF 3 COOD as the solvent.…”

“…(E)-3-styrylquinolin-4(1H)-ones 1a-1k and 1t were prepared according to the literature procedure (Scheme 1). 1,2 POCl 3 (123.4 mmol) was added dropwise to 25 mL dry N,N-dimethylformamide (DMF) at 0 o C under argon, and the mixture was stirred for 15 min at room temperature. Then a solution of 3 1-(2-aminophenyl) ethanones (20.6 mmol) in dry DMF (3 mL) was added dropwise.…”