1982
DOI: 10.1097/00000478-198212000-00003
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An immunoperoxidase study of S-100 protein distribution in normal and neoplastic tissues

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1982
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Cited by 569 publications
(150 citation statements)
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“…Among the immunohistochemical markers for nerve sheath cells, S-100 protein was introduced in immunohistochemistry very early and is still a useful marker for Schwann cells (15). Some studies have reported immunoreactivity of EMA in peri- neurial cells and their tumors (3,16,17).…”
Section: Discussionmentioning
confidence: 99%
“…Among the immunohistochemical markers for nerve sheath cells, S-100 protein was introduced in immunohistochemistry very early and is still a useful marker for Schwann cells (15). Some studies have reported immunoreactivity of EMA in peri- neurial cells and their tumors (3,16,17).…”
Section: Discussionmentioning
confidence: 99%
“…I In addition, it has been found in tissues outside the nervous system, including the interstitial cells in the pineal gland," satellite cells of the adrenal medulla,' stellate cells of the adenohyp~physis,'~ melanocytes and Langerhans' cells of the normal human skin,2 interdigitating reticulum cells of the lymph node," chondrocytes," and in tumors derived from these cell types. 13. 143 17, It also has been demonstrated in some neurons of the central nervous ~y s t e m ,~ and in tumors derived from these in Schwann cells of the peripheral nervous system, and in tumors of nerve sheath^.…”
mentioning
confidence: 98%
“…S-100 or like immunoreactants, on the other hand, were found to also exist in nonglial cells such as chondrocytes (STEFANSSON et al, 1982b), Langerhans cells of the human skin NAKAJIMA et al, 1982a) and fat cells (NAKAJIMA et al, 1982c). Along with these cells, the present authors preliminarily recognized that certain cells of mesenchymal origin are reactive to anti-S-100 antisera (IWANAGA et al, unpublished).…”
mentioning
confidence: 55%