Efforts towards attainment of sustainable economic growth and food security in Kenya are under increasing threats due the adverse effects of climate change. This study therefore, sought to assess the vulnerability of maize production to climate change in major maize producing counties of Kenya's Rift Valley region, using the indicator approach. Climate data including monthly rainfall, maximum and minimum temperature was obtained from Kenya Meteorological Department. The Sen's Slope Estimator was used to determine the rate of change of rainfall and temperature (1981-2010), which constituted the exposure indicators. The Standardized Precipitation Index (SPI) was used to determine the frequency of extreme climate events that formed part of exposure variables. As for the socioeconomic and biophysical data sets, sensitivity indicators included demographic and ecological sensitivity variables while adaptive capacity variables encopmassed social capital, literacy rate, financial capital and physical capital. Sensitivity and adaptive capacity data was obtained from Kenya Bureau of Statistics, Ministry of agriculture and Fisheries and Tegemeo Institute of Agricultural Policy and Development. After normalization, Principal Component Analysis (PCA) was used to assign weights to the indicators. Subsequently, the normalized values of each variable were multiplied with their respective weights as obtained from PCA and later aggregated to obtain Exposure, sensitivity, adaptive capacity and vulnerability indices Trans Nzoia had the least exposure index (0.19) and second highest adaptive capacity(2.59) which made it record the lowest vulnerability index of-0.212. Narok recorded the highest vulnerability index of 1.51 with the peak exposure (1.03) and least adaptive capacity (-2.28). Nakuru had the second highest vulnerability index (0.35) while Uasin Gishu recorded the second least vulnerability index (-0.12). Generally, counties with considerable socioeconomic development recorded high adaptive capacity which reduced their vulnerability significantly. Hence, in order to cushion most vulnerable maize producing counties, climate change policies and strategies should prioritize adaptive capacity enhancement through socio economic development initiatives such as irrigation, rural infrastructural development and educational programs.