An original approach for lipophilic natural products extraction: Use of liquefied n-butane as alternative solvent to n-hexane

Rapinel, Vincent; Rombaut, Natacha; Rakotomanomana, Njara; Vallageas, Alain; Cravotto, Giancarlo; Chémat, Farid

doi:10.1016/j.lwt.2016.10.003

Cited by 38 publications

(20 citation statements)

References 45 publications

(38 reference statements)

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“…In particular, propane, n-butane or dimethyl ether (DME) as liquified solvents have been extensively investigated for the extraction of fats and oils, antioxidants and aromas. [38][39][40][41][42][43][44][45][46][47][48] Zanqui et al 49 proposed n-propane as a solvent for the extraction of chia (Salvia hispanica L.) oil, resulting in a good extraction yield (28.16%) similar to the Soxhlet method and SC CO 2 , within a short time period (1 h). Moreover, the oil extracted using n-propane showed the best oxidation stability and the highest contents in polyunsaturated fatty acids (829 mg g −1 oil), particularly, omega 3 (628 mg g −1 oil) and omega 6 (201 mg g −1 oil).…”

Section: Applicationsmentioning

confidence: 99%

A review of sustainable and intensified techniques for extraction of food and natural products

et al. 2020

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Section: Applicationsmentioning

confidence: 99%

A review of sustainable and intensified techniques for extraction of food and natural products

et al. 2020

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“…Due to many different structures, plant terpenoids possess lipophilic or hydrophilic compounds [37]. Hexane is a non-polar solvent and therefore suitable to extract lipophilic compounds [38]. [23].…”

Section: Phytochemical Constituentsmentioning

confidence: 99%

Antimicrobial activity of selected plants against fungal species isolated from South African AIDS patients and their antigonococcal activity

Maema

Potgieter

Masevhe

et al. 2020

Journal of Complementary and Integrative Medicine

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BackgroundSexually transmitted infections continue to be a major health concern in sub-Saharan Africa where antimicrobial drugs are becoming ineffective due to increasing resistance. Many healthcare seekers in lower socio-economic settings depend on invasive alien plants administered by traditional health practitioners to treat sexually transmitted infections.MethodsRoots of selected plants were analysed for phytoconstituents using standard methods. Both the disc diffusion model and microdilution technique were used to determine the inhibition zone and minimum inhibitory concentration (MIC) of plant extracts against six clinical fungal strains and standard strain of Neisseria gonorrhoea. One-way ANOVA was used to find significant differences.ResultsDifferent phytoconstituents such as alkaloids, steroids, cardiac glycosides, terpenes, flavonoids, tannins and saponins were qualitatively detected, depending on plant species. Acetone extracted the highest number of phytoconstituents in Senna didymobotrya, while methanol revealed most from Ricinus communis. Senna didymobotrya showed significant inhibition against Candida glabrata, C. krusei, C. parapsilosis and C. tropicalis. Dichloromethane extract of Catharanthus roseus and methanol extract of S. didymobotrya demonstrated excellent MIC values of 0.03 and 0.08 mg/mL, respectively, against C. glabrata. Catharanthus roseus, Opuntia ficus-indica and Ricinus communis demonstrated moderate to good antigonococcal activity, with all exhibiting more than 63% inhibition. Catharanthus roseus had the best antigonococcal activity with a moderate MIC value of 0.63 mg/mL.ConclusionSome of the plant extracts demonstrated potency towards clinically isolated fungal strains and against N. gonorrhoea, which validate the notion that some of the species need further pharmacological studies for isolation and characterisation of active compounds.

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“…Another option is the use of subcritical solvents such as liquefied gases (e.g. n-butane), which may ally low polarity and facile solvent elimination by decompression at or close to room temperature (Rapinel et al, 2017). However, safety issues must be addressed for these new solvents.…”

Section: Alternative Solventsmentioning

confidence: 99%

Extraction of bioactives from fruit and vegetables: State of the art and perspectives

Renard

2018

LWT

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Fruit and vegetables are rich in bioactive compounds that contribute to the prevention of a number of degenerative diseases. These components are also present, often in even higher concentrations, in the co-products from fruit and vegetable processing. Such fact, makes these co-products an attractive source for the extraction of bioactives, turning the extraction itself into an attractive valorization strategy for these co-products. There has been recently renewed interest in extraction methods, notably with a process intensification using physical phenomena and the search for alternative solvents. This paper will present the main bioactives in fruit and vegetables, and their co-products, and the precautions to preserve these molecules in the food processing chain, with a main focus on the pros and cons of recently proposed extraction developments, particularly on extraction mechanisms, sample pre-treatment, and solvent choice.

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An original approach for lipophilic natural products extraction: Use of liquefied n-butane as alternative solvent to n-hexane

Cited by 38 publications

References 45 publications

A review of sustainable and intensified techniques for extraction of food and natural products

A review of sustainable and intensified techniques for extraction of food and natural products

Antimicrobial activity of selected plants against fungal species isolated from South African AIDS patients and their antigonococcal activity

Extraction of bioactives from fruit and vegetables: State of the art and perspectives

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