An overview of epidemiological studies on seasonal affective disorder

Magnusson, A.

doi:10.1046/j.0902-4441.2000..x

Cited by 97 publications

(123 citation statements)

References 31 publications

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“…*, **, and *** indicate significance at the 10%, 5%, and 1% levels, respectively, based on 2-sided tests. identify the seasonally varying risk-aversion effect, distinct from other seasonal influences, is to consider an implication of the hypothesis that net exchanges should be more pronounced the further the market is away from the equator, consistent with the clinical observation by Magnusson (2000) and others that the prevalence of seasonal depression generally increases with distance from the equator. The averageÔR t value across the U.S. equity and hybrid fund class net exchanges (based on values in Table 4) is approximately −0.08, whereas the average onset/recovery coefficient across the Canadian equity and hybrid fund classes net exchanges is approximately −0.14 (based on the values in Table 5).…”

Section: Table 5 Regression Results For Canadian Asset-class Net Exchmentioning

confidence: 99%

“…Individuals may begin recovering early in the new year, as the days lengthen, although most experience symptoms until spring (see Lam (1998b) and Young et al (1997)). Further, studies indicate that these seasonal changes in mood are more prevalent at higher latitudes (see, e.g., Magnusson (2000)) and that symptoms are milder close to the equator (see, e.g., Rosenthal et al (1984)). …”

Section: The Link Between Seasons and Risk Takingmentioning

confidence: 99%

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Seasonal Asset Allocation: Evidence from Mutual Fund Flows

Kamstra¹,

Kramer²,

Levi³

et al. 2017

J. Financ. Quant. Anal.

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We analyze the flow of money between mutual fund categories, finding strong evidence of seasonality in investor risk aversion. Aggregate investor flow data reveal an investor preference for safe mutual funds in autumn and risky funds in spring. During September alone, outflows from equity funds average $13 billion, controlling for previously documented flow determinants (e.g., capital-gains overhang). This movement of large amounts of money between fund categories is correlated with seasonality in investor risk aversion, consistent with investors preferring safer (riskier) investments in autumn (spring). We find consistent evidence in Canada and also in Australia, where seasons are offset by 6 months.

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Section: Table 5 Regression Results For Canadian Asset-class Net Exchmentioning

confidence: 99%

Section: The Link Between Seasons and Risk Takingmentioning

confidence: 99%

Seasonal Asset Allocation: Evidence from Mutual Fund Flows

Kamstra¹,

Kramer²,

Levi³

et al. 2017

J. Financ. Quant. Anal.

View full text Add to dashboard Cite

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“…Knowledge that the biomarker has been engaged then allows for assessment of whether an adequate number of phenotypes have been targeted in clinical trials with symptom burden as the primary outcome. In the present investigation, the biomarker identified provides opportunities to create novel prevention methods for SAD: it is clear that the environmental combination of seasonal variables, including light, temperature, and humidity, influence 11 C]DASB 5-HTT BP ND could then be incorporated into larger scale clinical studies as prevention strategies in high-risk communities, such as those in Northern latitudes where SAD prevalence exceeds 6% (Magnusson, 2000).…”

Section: Severe Sadmentioning

confidence: 99%

“…The annual prevalence of SAD is typically 1-6%, with the highest rates occurring at more extreme latitudes (Magnusson, 2000). Although information about SAD is accumulating, a critical gap is the lack of direct brain investigations of this illness.…”

Section: Introductionmentioning

confidence: 99%

Increased Seasonal Variation in Serotonin Transporter Binding in Seasonal Affective Disorder

Tyrer

Levitan

Houle

et al. 2016

Neuropsychopharmacol

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Seasonal affective disorder (SAD) is highly prevalent with rates of 1-6% and greater prevalence at more extreme latitudes; however, there are almost no direct brain investigations of this disorder. In health, serotonin transporter binding potential (5-HTT BP ND ), an index of 5-HTT levels, is greater throughout the brain in fall-winter compared with spring-summer. We hypothesized that in SAD, this seasonal variation would be greater in brain regions containing structures that regulate affect such as the prefrontal and anterior cingulate cortices (PFC and ACC). Furthermore, given the dimensional nature of SAD symptoms, it was hypothesized that seasonal fluctuation of 5-HTT BP ND in the PFC and ACC would be greatest in severe SAD. Twenty SAD and twenty healthy participants underwent [11 C]DASB positron emission tomography scans in summer and winter to measure seasonal variation in [ 11 C]DASB 5-HTT BP ND . Seasonal increases in [11 C]DASB 5-HTT BP ND were greater in SAD compared with healthy in the PFC and ACC, primarily due to differences between severe SAD and healthy (severe SAD vs healthy; Mann-Whitney U, U = 42.5 and 37.0, p = 0.005 and 0.003, respectively; greater magnitude in severe SAD of 35.10 and 14.23%, respectively), with similar findings observed in other regions (U = 40.0-62.0, p = 0.004-0.048; greater magnitude in severe SAD of 13.16-17.49%). To our knowledge, this is the first brain biomarker identified in SAD. This creates a new opportunity for phase 0 studies to target this phenotype and optimize novel prevention/treatment strategies for SAD.

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“…Within the recurrent depressed population, 10-20% of all cases follow a seasonal onset pattern (Magnusson, 2000). Several longitudinal studies have supported the observation that SAD episodes recur in a predictable pattern (Graw, Gisin, & WirzJustice, 1997;Sakamoto et al, 1995).…”

Section: Introductionmentioning

confidence: 85%

Changes in cognitive-behavioral constructs across treatment modalities for seasonal affective disorder: Cognitive-behavioral therapy, light therapy and their combination

Lindsey¹

2003

PsycEXTRA Dataset

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An overview of epidemiological studies on seasonal affective disorder

Abstract: The actuality of seasonal variation in mood has been documented thoroughly by both retrospective and prospective studies. In the general population, depressive symptoms peak in winter, and the most extreme form of this disposition, SAD, appears to be a relatively common disorder.

Cited by 97 publications

References 31 publications

Seasonal Asset Allocation: Evidence from Mutual Fund Flows

Seasonal Asset Allocation: Evidence from Mutual Fund Flows

Increased Seasonal Variation in Serotonin Transporter Binding in Seasonal Affective Disorder

Changes in cognitive-behavioral constructs across treatment modalities for seasonal affective disorder: Cognitive-behavioral therapy, light therapy and their combination

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