The recent progress of in-vehicle communication networks has been highlighted by the intensive investigation of optical packet communication systems using a modulation and detection device. This paper proposes a burst-mode driver circuit with an on-chip bias switch to achieve a stable and quick response in bias switching operation. The proposed circuit comprises a driver core and two types of bias circuits. Moreover, the proposed circuit changes output bias voltages using a MOS transistor as a switch. To verify the operating principle, we design the proposed circuit using a high-voltage tolerant 65-nm CMOS technology and obtain the post-layout simulations and measurement results. As a result, we achieve quick bias switching operation with 90% faster response time than the conventional one.