An Unusual Cause of Death From Cancer

Abstract

AN UNUSUAXJ CAUSE OF DEATH FROM CANCER. )I~ã nd apparently composed of pleura which is thickened in that region. Through this clear area the details of the ribs and scapula can be made'out.; tllere is very little evidence of dMtail of 'the lung. Tlle lower margin is irregular and ill defined, and slhows strands of denser tissue with clear areas between. The general 'appearance is strongly suggestive of air in the pleural cavity. It has not tlle typical appearance of a large pneumothorax, and is more typical of gas within a distended' viscus. The nature of the appearances described was clearly indicated when an opaque meal was given to the patient and a series of radiograms composed. The wlhole of the meal was seen to be retained on the left side, extending from a sharply defined point at the level of the first lumbar vertebra, and extending upwards to a point at tlle level of the seventlh dorsal vertebra. The opaque shadow, with tlje gas-distended. space above it, occupied about ''to-thirds of the total thoracic space on the left' side. Above the shadow of the' opaque material in the viscus was a clear area, antl at a still hiigher level a dome-shaped structure representing the limitations of the above-described air space. This structure most probably consisted of tllickened pleura, and formed a limiting membrane for the herniated stomaclh.IThe x-ray examination with the opaque food showed clearly that the stomach was situated in tlle thoracic cavity; the irregularity of the diaphragm and the gas formation seen in tlhe earlier pictures are suggestive of tlhe diagnosis, but no positive opinion could be expressed nntil the stomach lhad been filled witlh the opaque food. It is interesting to note that later negatives showed that limitiug structure of tlle air space was capable of contracting to some extent upon the stomach, and -tlhis is shown-by the negatives, in wllich the stomach is seen to contain less of thje food than in those of an earlier period..The radiogramns taken on June 28th, 1921, after the patient had been operated upon, slhow a different appearance from those taken when he was first examined.The upper suilaces of thle diaplhragm are practically on the same level. On both sides of the chest thle lung detail is well seen; there is no sign of the gas, the heart now occupies a normal position, in strong contrast to tlhe position it assumed in the first pictures, in which it was displaced well over to the righ-t. The lungs show an increase of the root shadows, and there is evidence of enlarged glands at tlle roots with peribronchial thickening extending into the lung substance.

Cardiac Metastasis in a Living Patient With Laryngeal Squamous Cell Carcinoma

“…Primary treatment involved surgery in five cases (25%) [ 11 , 15 ], radiotherapy in one case (5%) [ 6 ], combination therapy with surgery and radiation in five cases (25%) [ 8 , 9 , 12 , 13 , 16 ], and a combination of surgery with chemoradiation in two cases (10%) [ 1 ], including current case. Two patients had tracheostomy performed for symptom relief [ 3 , 14 ]. Most cases (80%) had cardiac metastases discovered within two years after the initial diagnosis, except one, where metastatic disease to the heart was diagnosed five years later [ 16 ].…”

“…Tumors involving the heart and pericardium are far more likely to be secondary (metastatic) than primary, occurring in up to 18.3% of patients with metastatic disease [ 2 ]. Cardiac metastasis of laryngeal cancer is a rare condition, with one of the earliest reports of infiltrative cardiomyopathy secondary to laryngeal carcinoma written by Linell et al in 1922 [ 3 ], and only several cases reported in the literature over the past century. We report a case of laryngeal squamous cell carcinoma (SCC) with subsequent metastatic disease to the heart.…”

Med språket genom tillvaron: En introduktion till dialogiska perspektiv på språkande, tänkande och kommunikation

“…Vetenskaparna har då inte alltid varit helt konsekventa i sin sekularisering*. Man bygger inte bara på naturvetenskap och 45 Jfr Linell (2017a). Generativismen har stora problem att förklara hur ett så abstrakt språk som teorin antar "finns", kan ha utvecklats evolutionärt.…”

“…Chomsky har i en intervju citerad av MacNeilage (2008: 3) deklarerat att språket inte kan förklaras; "det tycks bara vara så att det finns". Generativismen är emellertid inte ensam bland språkteorier om att ha vetenskapsteoretiska problem (se vidare Linell, 2017a). Somliga problem delas med strukturalismen i stort (t.ex.…”

Neuropathology in Canada: The First One Hundred Years

“…His subsequent MD thesis, awarded in 1920, concerned the anatomy of the peripheral nervous system 53 . He showed some early interest in pathology, publishing an autopsy report of carcinoma of the larynx 54 , but had no formal training in pathology. In 1923 he was recruited to the University of Toronto to teach neuroanatomy 55 .…”