Anal Carcinoma: Prognostic Value of Endorectal Ultrasound (ERUS). Results of a Prospective Multicenter Study

Abstract

This muticenter prospective study demonstrated the superiority of ERUS-based staging over traditional clinical staging in the prediction of important outcomes such as local tumor recurrence and patient survival.

Assessment of the accuracy of transrectal ultrasonography in anorectal neoplasia

“…In the authors' data set this would result in a significant improvement in the overall accuracy of TRUS, yielding a weighted κ value of 0·94. This adjustment may allow TRUS results to provide a better reflection of clinical management decision-making 10,20,21 .…”

Anal carcinomas: the role of endoanal ultrasound and magnetic resonance imaging in staging, response evaluation and follow-up

“…EAUS has been shown to be superior to MRI in the detection of small superficial tumours of the anal canal [16]. Staging systems on EAUS have been suggested [13,21] which emphasise depth of invasion over size of tumour (Table 3), similar to the staging classification in rectal carcinoma. This staging system is not as widely used as the AJCC staging system.…”

“…13 Progression of disease following chemoradiation on MRI: a Axial T2-weighted MRI pre-treatment demonstrate a 4-cm-long anal canal tumour involving the left puborectalis (white arrow); b Axial T2-weighted MRI taken 7 months later postchemoradiation shows resistance to treatment with disease progression-the mass has further extended through the left puborectalis muscle (white arrow). There is a new right inguinal nodal metastasis (black arrow) sufficient time frame to allow for resolution of oedema and for accurate ultrasound imaging [13]. Serial follow-up examination with EAUS can monitor changes in the size of residual scar tissue and detect local recurrence [23].…”

“…This does not take into account sphincter muscle involvement which is an important prognostic factor [11]. In the last decade there has been increasing use of endoanal ultrasound (EAUS) and magnetic resonance imaging (MRI) for locoregional staging [12][13][14][15]. There appears to be only one paper to date [16] that directly compares EAUS (using 2-dimensional imaging) with MRI in the primary staging of anal carcinoma.…”

Hallazgos en endosonografía anorrectal en una cohorte prospectiva

“…De igual forma, la importante frecuencia de indicación en pacientes con neoplasia maligna rectal confirmada habla de la aceptación a nivel nacional y regional que se le está dando a este diagnóstico por parte de grupos interdisciplinarios de oncología, donde la endosonografía juega un papel fundamental a la hora de complementar otras ayudas diagnósticas para estadificación locorregional y planeamiento adecuado de la terapia (4,9,(19)(20)(21)(22).…”