Analgesic activity of ethanolic extract of flower of <i>Lantana camara</i>

Punasiya, Rakesh; Choudhary, Jyoti; Pillai, Sujit

doi:10.5958/0975-4377.2017.00029.5

Cited by 2 publications

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“…camara is an ornamental plant that belongs to the Verbenaceae family and has anti-cancerous, antihypertensive, anti-inflammatory, and antimicrobial properties. 17 According to the published report the ethanol extract of L. camara possess a cytotoxic effect against human lung cancer cell lines (A-549). 18 In the current work, the anticancer activity of L. camara extracts was observed on MDA-MB-231, A-549, PC-3 and Hep-G2 cell lines also.…”

Section: Discussionmentioning

confidence: 99%

In-vitro Anticancer Activity of Various Plant Extracts

Mishra¹,

Dash²,

Mohapatra³

2023

IJPQA

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Herbal medicinal plants have been explored for a variety of pharmacological properties but still a large number of phytoconstituents are still unexplored. The manuscript aims to assess the anticancer property of Leucas cephalotes (Roth) Spreng, Acalypha indica L. and Lantana camara L. extracts on MDA-MB-231, A-549, PC-3 and Hep-G2 cell lines. The ethanol extract of the selected plants was explored for anticancer activity by SRB assay. Since L. camara exhibited promising activity, this plant’s successive extraction in diff erent extracts (n-hexane, chloroform, ethanol and hydroalcoholic) was further studied. All the extracts were screened for anticancer activity by SRB assay on MDA-MB-231 and A-549 cell lines. Additionally, the apoptotic assay was carried out on n-hexane and chloroform extracts on A-549 cell lines. GCMS also analyzed both extracts for characterization of the phytoconstituents. Obtained data indicate that n-Hexane and chloroform extracts of L. camara showed promising anticancer activity on MDA-MB-231 and A-549 cell lines. Both extracts also induced apoptosis in A-549 cell line. GC-MS data of L. camara extracts revealed the presence of 25 and 19 compounds in n-hexane and chloroform extract, respectively. The present study shows that L. camara has strong anticancer properties against lung cancer cell lines compared to breast, prostate, and hepatoma cancer cell lines

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Section: Discussionmentioning

confidence: 99%

In-vitro Anticancer Activity of Various Plant Extracts

Mishra¹,

Dash²,

Mohapatra³

2023

IJPQA

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MTT Assay on Anticancer properties of the different extracts of roots of Lantana camara Linn.

Ali,

Malipatil,

Ahmed

2024

RJPT

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Lantana camara, considered a weed is an evergreen plant found throughout the world. Traditionally it has been used in the treatment of various ailments and has been supported by scientific investigation. Phytoconstituents present in almost all parts of this plant have been reported in various literature. This study has been done on the root part of Lantana camara, the dried and powdered root was subjected to continuous solvent extraction with Hexane followed by Ethyl Acetate and Methanol. Ethyl Acetate and Methanol extracts were evaluated for anticancer activity by MTT assay, MCF7 cell line was used with Cisplatin a known anti-cancer drug as a standard reference, and the measurements were carried out at wavelengths 570 and 630nm. The percentage of growth inhibition was calculated. The concentration of test extract needed to inhibit cell growth by 50% (IC50) value generated from the dose-response curve. IC50 values of Ethyl Acetate extract were greater than 500µg/ml and Methanol extract 450.05µg/ml.

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Analgesic activity of ethanolic extract of flower of Lantana camara

Cited by 2 publications

References 0 publications

In-vitro Anticancer Activity of Various Plant Extracts

In-vitro Anticancer Activity of Various Plant Extracts

MTT Assay on Anticancer properties of the different extracts of roots of Lantana camara Linn.

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