Análise da taxa de transmissão vertical do HIV e fatores de risco materno-fetais em crianças expostas nascidas em centro de referência do estado de Goiás

Rosa, Renata Rodrigues; Albuquerque, Maly de; Filho, Ricardo Vieira Teles; Abe, Guilherme de Matos; Marques, Solomar Martins; Costa, Paulo Sucasas

doi:10.11606/issn.1679-9836.v100i5p449-454

Cited by 2 publications

(3 citation statements)

References 8 publications

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“…Regarding childbirth, VT occurred in 39.6% (21) of those who underwent prophylaxis during childbirth and in 60.3% (32) of those who did not undergo ART. Several national and international studies have demonstrated that the association of prophylaxis during prenatal care and during childbirth are effective prophylactic measures for the reduction of vertical transmission 1 , 9 , 19 , 28 . A study conducted in Alagoas State, assessing 76 pairs of mother and child, verified that 19.0% of infected pregnant women did not receive ART prophylaxis during pregnancy and 22% did not receive it during childbirth, resulting in a vertical transmission rate of 6.6% 28 .…”

Section: Discussionmentioning

confidence: 99%

“…In 2019, there were approximately 38 million persons living with HIV worldwide, of which 1.8 million were children from 0 to 14 years old 1 . In Brazil, in 2019, there were 43,312 new HIV cases notified on the Notifiable Diseases Data System (SINAN), of which 11,879 were females and 8,268 were pregnant women 2 .…”

Section: Introductionmentioning

confidence: 99%

“…Despite the advances in the prevention of vertical transmission, data point out that, in 2019, there were 1.8 million children worldwide living with HIV and over 150,000 were recently infected 1 , 3 . In Brazil, in 2015, in all regions of the country, there were 7,901 cases notified of infected pregnant women and 62 cases of infection with HIV in children who were ≤ 5 years old, and it is estimated that vertical transmission on a national level is currently between 15% and 24% 3 , 21 .…”

Section: Introductionmentioning

confidence: 99%

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Vertical transmission of HIV to neonates in a reference hospital in Northeastern Brazil from 2013 to 2017

Figueredo,

Monteiro,

Batista

et al. 2023

Rev. Inst. Med. trop. S. Paulo

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The aim of this study was to estimate the rate of Mother-to-child Transmission (MTCT) of HIV to neonates in a reference university hospital in Sao Luis city, the capital of Maranhao State (MA), evaluating MTCT-associated factors. A retrospective cohort study based on data from the Notifiable Diseases Data System (SINAN) was carried out and included all HIV-exposed neonates notified from 2013 to 2017 by the university hospital. The study population comprised 725 HIV-exposed neonates, of whom 672 neonates were exposed and uninfected, and 53 were exposed and infected. The estimated rate of MTCT in the period of 2013 to 2017 was 7.3%. Most pregnant women were ≥ 20 years old (86.9%), reported ≥ 8 years of schooling (53.2%), reported full-time or independent paid work (46.9%) and were residents in other cities of the state (61.7%). Regarding healthcare, 86.3% received prenatal care, 74.6% received Antiretroviral Therapy (ART) as prophylaxis during pregnancy, 81.8% received ART prophylaxis during childbirth and 78.1% underwent cesarean section. Among the neonates, 92.8% received ART prophylaxis and 94.3% were not breastfed. Despite these variables, the 7.3% MTCT rate found in this study makes it clear that the interventions recommended by the Ministry of Health were not fully adopted.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Vertical transmission of HIV to neonates in a reference hospital in Northeastern Brazil from 2013 to 2017

Figueredo,

Monteiro,

Batista

et al. 2023

Rev. Inst. Med. trop. S. Paulo

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Risks of Mother-to-Child Transmission of Hiv

Souza¹,

Araújo²,

Silva³

et al. 2022

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Vertical transmission is a condition in which the virus is infected from mother to child and can have some consequences and risks during pregnancy and at the time of delivery. It is estimated that the incidence of vertical transmission occurs in 25% of pregnancies of infected women when there are no prophylactic measures and therapeutic interventions, resulting in high rates of mortality and disease progression. Contact with contaminated fluids can lead children to contract the virus in the first few months of life. The factors involved include several failures in the health system and maternity. Thus, the present study is based on the following justification: In health services and in the social context, there are difficulties and gaps that contribute to the risk factors of vertical transmission of HIV, constituting negative results for the control of the disease. In view of this, the objective of this research is to identify in the literature which are the existing difficulties that influence the prophylactic measures of vertical transmission. This study was carried out through an integrative literature review, through a survey of data in the scientific bases: LILACS, SCIELO and BDENF. The results obtained indicate that the failure to take prophylactic measures during pregnancy, due to negligence in prenatal consultations, is considered one of the aggravating factors for the risk of VT. Without early diagnosis, without knowledge of the virus, the pregnant woman does not undergo treatment with antiretroviral medication, with this, the immune system is more vulnerable to weakening and risks of complications during pregnancy.

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Análise da taxa de transmissão vertical do HIV e fatores de risco materno-fetais em crianças expostas nascidas em centro de referência do estado de Goiás

Cited by 2 publications

References 8 publications

Vertical transmission of HIV to neonates in a reference hospital in Northeastern Brazil from 2013 to 2017

Vertical transmission of HIV to neonates in a reference hospital in Northeastern Brazil from 2013 to 2017

Risks of Mother-to-Child Transmission of Hiv

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