This chapter aims to describe how the alignment of organizational competencies with the dimensions of the triple bottom line (TBL) in companies of the Brazilian chemical sector are integrated in the business strategy. This study used a methodological approach to qualitative research, the multiple case study strategy, covering three major producing companies in the Brazilian chemical industry: Braskem, Solvay, and Beta (fictitious name). As regards the scale interactions of organizational competence between the environmental pillars, economic, and social TBL, the analysis was done taking as a basis the properties of eco-efficiency, environmental justice, and social justice. Besides the three skills characterized by TBL interaction model for sustainable development, the competence of eco-innovation was evident, with the internal factors that influence: strategic dimension of eco-innovation, collaboration networks, support of management leadership and top management.