Communication, media and informatics technologies that are increasingly rapidly developing internet users in Indonesia are potential for business people in Indonesia, where as the rapid growth of internet users, this also encourages e-commerce growth in Indonesia. Global information has influenced the ways and patterns of business activities in the trade industry, social and political governance. One of the technological advances that are widely used by people, organizations and companies is the internet. The purpose of this research is to know the effects of uncertainty reduction and benefits on purchasing airplane tickets online. The research method used is a descriptive method and explanatory survey. This research was conducted in Indonesia. The sample selection was done by using a convenience sampling technique with the number of samples of 50 respondents. A statistical method for data test using SPSS 22 for windows program. By using multiple linear regression analysis, the results show that uncertainty reduction has a partial effect on purchase decisions but not for online purchase benefits, and both of the variables simultaneously affect the purchase decision.