Due to the relatively low load-carrying capacity, low-viscosity lubricated bearings can easily operate in a mixed-lubrication regime. Furthermore, low lubricant viscosity may cause local turbulence in the area with relatively thick film. To analyze the influence of local turbulence on the transient characteristics of mixed-lubrication bearings, a simulation approach for unsteady mixed-lubrication bearings considering local turbulence effects is proposed. Transient journal center locations are solved via journal dynamic equations and numerical integration. The ratio of the film thickness to the roughness determines whether each node of the bearing is in the mixed-lubrication area or the pure hydrodynamic lubrication area. The liquid film in the mixed-lubrication area is analyzed by a transient average Reynolds equation to account for the surface roughness effect. A liquid film in the hydrodynamic lubrication area is analyzed by a transient generalized Reynolds equation to consider local turbulence. The transient average Reynolds equation and transient generalized Reynolds equation are derived in a form convenient for coupling with the governing equations of the journal center. The proposed model is experimentally validated. The influence of local turbulence on unsteady mixed-lubrication bearings is analyzed. The results show that local turbulence and asperity contact can coexist in low-viscosity lubricated bearings, even if the journal speed is relatively low. In the mixed-lubrication regime, local turbulence increases the minimum film thickness and decreases the friction coefficient, as well as the journal speed at which the mixed-lubrication transitions to hydrodynamic lubrication.