Analytical Supercritical Fluid Extraction of Natural Products

Modey, William K.; Mulholland, Dulcie A.; Raynor, Mark W.

doi:10.1002/(sici)1099-1565(199601)7:1<1::aid-pca275>3.0.co;2-u

Cited by 119 publications

(44 citation statements)

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“…SFE of flavors, fragrances and other natural products has been reviewed. These reviews have described a wide range of applications for the extraction of several groups of non-polar compounds, including essential oils, other flavor and fragrance compounds, medicinal compounds, lipids, carotenes and alkaloids, tocopherols and tocotrienols, as well as the global yield and quality of the extracts all of the plant materials investigated, and the possibility of their application in the food, cosmetics and pharmaceutical industries [4,7,11,[21][22][23][24][25][26][27][28][29][30]. The nature of extracted plant materials, the mathematical modelling of the process, and the choice of the appropriate model have been reviewed too [31].…”

Section: Supercritical Fluid Extraction Of Flavors and Fragrancesmentioning

confidence: 99%

“…A total of 44 aroma compounds were identified in Zhenjiang aromatic vinegar SFE extract. Acetic acid (15), ethyl acetate (16), furfural (17), phenethyl alcohol (18), tetramethylpyrazine (19), 3-hydroxy-2-butanone (20) and benzaldehyde (21) were the main aroma compounds in the vinegar SFE extract (Figure 3) [46].…”

Section: Supercritical Fluid Extraction Of Flavorsmentioning

confidence: 99%

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Supercritical Fluid Extraction of Plant Flavors and Fragrances

2013

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Supercritical fluid extraction (SFE) of plant material with solvents like CO 2 , propane, butane, or ethylene is a topic of growing interest. SFE allows the processing of plant material at low temperatures, hence limiting thermal degradation, and avoids the use of toxic solvents. Although today SFE is mainly used for decaffeination of coffee and tea as well as production of hop extracts on a large scale, there is also a growing interest in this extraction method for other industrial applications operating at different scales. In this review we update the literature data on SFE technology, with particular reference to flavors and fragrance, by comparing traditional extraction techniques of some industrial medicinal and aromatic crops with SFE. Moreover, we describe the biological activity of SFE extracts by describing their insecticidal, acaricidal, antimycotic, antimicrobial, cytotoxic and antioxidant properties. Finally, we discuss the process modelling, mass-transfer mechanisms, kinetics parameters and thermodynamic by giving an overview of SFE potential in the flavors and fragrances arena.

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Section: Supercritical Fluid Extraction Of Flavors and Fragrancesmentioning

confidence: 99%

Section: Supercritical Fluid Extraction Of Flavorsmentioning

confidence: 99%

Supercritical Fluid Extraction of Plant Flavors and Fragrances

2013

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“…It is important to note that, the solubility of analytes in a solid matrix in supercritical fluid extraction is a major factor determining the extraction efficiency. The solubility is generally controlled by the volatility of substance, which is a function of temperature and solvation effect of the supercritical fluid, which is a function of fluid density [18,19]. Therefore, it is difficult to predict the effect of temperature.…”

Section: Analysis Of Response Surfacementioning

confidence: 99%

Optimization of Extraction Condition for Supercritical Carbon Dioxide (SCCO 2) Extraction of Strobhilantes crispus (Pecah Kaca) Leaves by Response Surface Methodology

Md Salleh

2012

J Food Process Technol

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Supercritical carbon dioxide (SC-CO 2 ) extraction was used to obtain the bioactive flavonoid compounds of Strobilanthes crispus (Pecah Kaca). Process variables namely pressure, temperature and co-solvent flow rate were studied for optimization of the extraction yield and bioactive flavonoid compound of S. crispus by response surface methodology following a Box Behnken design of experiments. HPLC was performed to determine the major bioactive flavonoid compounds from S. crispus. The optimum value of yield extraction (6.55%) was obtained at pressure 200 bar, 50°C temperature and co-solvent flow rate of 5 g/min. Under the optimum conditions, eight flavonoid compounds were identified namely (+)-catechin, (-) epicatechin, rutin, myricetin, luteolin, apigenin, naringenin and kaempferol. The experimental extraction yield is in good agreement with the predicted one. The response surface methodology used in this study was able to predict the optimal extraction conditions for the extraction yield of bioactive flavonoid compounds from S.crispus leaves extract.

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“…Supercritical fluid extraction (SFE) has become the method of choice for the extraction of secondary metabolites from solid matrices such as plant material [9,10]. It represents an interesting alternative technique to conventional liquid-solid extraction (e.g.…”

Section: Introductionmentioning

confidence: 99%

Application of central composite designs in the supercritical fluid extraction of tropane alkaloids in plant extracts

et al. 1999

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Abstract. Central composite designs were used in the study of supercritical fluid extraction (SFE) of three tropane alkaloids : hyoscyamine and scopolamine from Datura candida x D. aurea hairy roots and cocaine from coca leaves (Erythroxylum coca). Several SFE parameters, such as pressure, temperature, the nature and percentage of the polar modifier were examined. The tropane alkaloid extraction yield was established as response. A comparison between the predicted and the experimental extraction yields was established in order to assess the prediction quality of the model. Response surfaces were drawn from the mathematical models and enabled to determine the optimal conditions and to visualise the method robustness. The behaviour of the compounds investigated was discussed in relation with the selected SFE parameters.

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Analytical Supercritical Fluid Extraction of Natural Products

Cited by 119 publications

References 0 publications

Supercritical Fluid Extraction of Plant Flavors and Fragrances

Supercritical Fluid Extraction of Plant Flavors and Fragrances

Optimization of Extraction Condition for Supercritical Carbon Dioxide (SCCO 2) Extraction of Strobhilantes crispus (Pecah Kaca) Leaves by Response Surface Methodology

Application of central composite designs in the supercritical fluid extraction of tropane alkaloids in plant extracts

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