Anemia in Type 2 Diabetes Mellitus in Absence of Renal Insufficiency

Pathak, Jaya; Vadodariya, Varoon; Jhala, Ami; Bhojwani, Deesha; Brahmbhatt, Niravkumar

doi:10.21276/ijcmr.2019.6.11.26

Cited by 3 publications

(2 citation statements)

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“…22 Some more studies done by Kaushik et al, Sajid et al and Pathak et al, reported 63%, 35.2% and 45.2% as their prevalence respectively. [23][24][25] The prevalence of our study was in concordance with many other studies conducted across the world. Urgent attention to screening of anaemia is required in the patients with type 2 diabetes which will further assist in early diagnosis and management of the patients.…”

Section: Discussionsupporting

confidence: 91%

Prevalence of anaemia and its correlation with glycosylated haemoglobin among patients with type 2 diabetes mellitus: an observational study

Verma

Sheikh

2021

Int J Adv Med

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Background: Anaemia and type 2 diabetes mellitus are two sides of a coin affecting the quality of life of the patients. Anaemia associated with diabetic status of the patients disturbs the exercise capacity, increases fatigue, anorexia, depression, cognitive dysfunction and decreased libido. Hence, we conducted a study to find the prevalence of anaemia among patients with type 2 diabetic patients and its correlation with glycosylated haemoglobin.Methods: An observational study was conducted in the department of medicine in a tertiary care hospital in Maharashtra. The data was collected from patients with type 2 diabetes attending the outpatient department during a span of 5 months (September 2020 to February 2021). The patients with pre-existing hypertension, chronic renal failure, congestive cardiac failure, stroke and other haematological disorders were excluded from the study. Patients on hormonal therapy, pregnant and lactating patients were also excluded from the study. Prior to the start of the study necessary permissions were taken from the institutional ethics committee. Relevant statistics were used to analyse the data.Results: The prevalence of anaemia in the present study was 45 (56.25%). Among these 45 patients 37 patients had normocytic normochromic anaemia, 6 cases of microcytic hypochromic anaemia and 2 cases of macrocytic anaemia. The mean haemoglobin levels among patients with Hba1c more than 7% was 9.7±1.12 and among Hba1c less than 7% was 12. 23±1.08 and this difference was statistically significant.Conclusions: About half of the patients were anaemic in the present study. Normochromic normocytic anaemia was the most common type of anaemia. There was significant association with levels of anaemia with Hb1ac in the present study.

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Section: Discussionsupporting

confidence: 91%

Prevalence of anaemia and its correlation with glycosylated haemoglobin among patients with type 2 diabetes mellitus: an observational study

Verma

Sheikh

2021

Int J Adv Med

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“…On comparing the anemic cases and controls in both genders, the Odds ratio for males and females was 2.14 and 2.04 respectively with P < 0.05. 28…”

Section: Discussionmentioning

confidence: 99%

Anemia profile in Diabetic patients with preserved renal function

Krishnamurthy

Kerekoppa²

2021

Asian J Med Sci

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Background: Diabetes is one of the largest global health emergencies of the 21st century. Prevalence of anemia in diabetic patients is two to three times higher than for patients with comparable renal impairment and iron stores in the general population. Aims and Objective: This study was done to analyse the prevalence of anemia and its profile in patients with preserved renal function. Materials and Methods: One-hundred diabetic patients with anemia with normal renal functions were selected. Complete blood count, peripheral blood smear, iron studies, vitamin B12 levels were assessed. Diabetic control was monitored by HbA1c. Patients were identified to have specific type of anemia, based on iron profile and vitamin B12 levels. Severity of anemia was also assessed. Appropriate statistical tests were applied to analyse the results. Results: Mean age of subjects in the study group was 53.4±13.6 years. The mean haemoglobin level was 9.41±2.18 g/dl. Out of the 100 cases, 43 patients had iron deficiency anemia, 40 patients had anemia of inflammation, and 8 patients had vitamin B12 deficiency, 8 patients had combined iron and vitamin B12 deficiency, and 1 patient had pancytopenia. Mean HbA1c was higher in iron deficient individuals with a significant p value and mean HbA1c was lower in Vitamin B12 deficient individuals. Among the cases, 16% had mild anemia, 61% had moderate anemia, and 23% had severe anemia. Severe anemia had a significantly lower HbA1c, which was statistically significant. Conclusion: According to our study, iron deficiency anemia was the commonest, followed by anemia of inflammation in diabetic patients with preserved renal function. Diabetes being a pro-inflammatory state had a higher incidence of anemia of inflammation compared to general population. We have to identify and acknowledge the higher prevalence of Anemia of Inflammation in diabetic patients in the absence of renal dysfunction.

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Anemia a Contributory Factor Affecting Quality of Life in Type 2 Diabete1s Mellitus Patients

Kashif

Iqbal

Ambreen³

et al. 2022

J Gandhara Med Dent Sci

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OBJECTIVES: The study aimed to determine the prevalence of anemia in type 2 diabetes mellitus patients and its effects on the quality of life in diabetic patients. METHODOLOGY: A cross-sectional study was conducted at the Department of Pathology, Government Naseer Ullah Khan Babar Memorial Hospital, Peshawar, Pakistan. All diabetic patients admitted to the medical ward were included in this study, and their blood samples were obtained in heparinised and EthyleneDiamineTetracetic Acid (EDTA) tubes by aseptic technique after informed consent. All samples were assessed for sugar levels and complete blood count. RESULTS: 118 diabetic patients were enrolled in this study, 66% of patients were females, and 34% were males. Female patients in age groups 1, 2 and 3 were more than males, and in age group 4, all patients were male. Anemia was found in about 79% of females and 21% of male patients. CONCLUSION: Albuminuria and renal insufficiency are important factors in understanding and investigations of anemia. Diabetic patients must be screened for anemia and treated accordingly to improve the quality of life in such patients and reduce morbidity and mortality rate.

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Anemia in Type 2 Diabetes Mellitus in Absence of Renal Insufficiency

Cited by 3 publications

References 16 publications

Prevalence of anaemia and its correlation with glycosylated haemoglobin among patients with type 2 diabetes mellitus: an observational study

Prevalence of anaemia and its correlation with glycosylated haemoglobin among patients with type 2 diabetes mellitus: an observational study

Anemia profile in Diabetic patients with preserved renal function

Anemia a Contributory Factor Affecting Quality of Life in Type 2 Diabete1s Mellitus Patients

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