Anesthesia and Pain Control

Bednarski, Richard M.

doi:10.1016/s0195-5616(89)50136-0

Cited by 6 publications

(2 citation statements)

References 592 publications

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“…the attempts to inhibit these responses by increasing the inhalant concentrations might induce severe cardiovascular and respiratory depression that, in turn, induce inadequate perfusion of vital organs even in young healthy patients. in asa 3 and 4 subjects, also light levels of inhalant anaesthetics may be too depressant and hemodynamic responses, such as tachycardia and hypertension, may occur even when anaesthetic concentrations of inhalant agents are high enough to prevent sensory, motor, and respiratory responses [4,31]. furthermore, there are findings suggesting that while halothane was able to block the cardiovascular response to incision in dose-dependent manner, increasing the concentrations of iso did not necessarily suppress this response [61].…”

Section: Discussionmentioning

confidence: 99%

A Novel and Effective Balanced Intravenous-Inhalant Anaesthetic Protocol in Swine by Using Unrestricted Drugs

et al. 2014

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Nowadays, because of increasing employment of swine for experimental studies and medical training, it is hopeful to investigate novel and effective anaesthetic protocols for preserving the animal welfare in medical investigation and concurrently improving the quality of research. Therefore, the aim of this study was to investigate a novel and effective anaesthetic protocol in swine undergoing major surgery, by translating know-how of combined anaesthesia from human protocols. Seven landrace swine were anaesthetized for three hours by a combined trial anaesthetic protocol (sedation: medetomidine, acepromazine, atropine and tramadol; induction: propofol, medetomidine and acepromazine; anaesthesia: isofluorane, propofol, medetomidine and acepromazine) and both clinical and haemodynamic parameters were compared with those of five swine anaesthetized with a control protocol (sedation: diazepam, ketamine and atropina; induction: diazepam and ketamine; anaesthesia: isofluorane). Both cardiac frequency (CF) and mean blood pressure (MBP) were significantly (P<0.05) more stable in trial protocol (CF: 78.3 ± 4.6-81.1 ± 5, MBP: 63.9 ± 10.7-96.4 ± 13.0) compared to control protocol (CF: 93.7 ± 5.5-102.5 ± 8.5, MBP: 71.0 ± 6.6-108.7 ± 7.2). The body temperature remained stable in trial protocol (°C: 36.9 ± 0.7-37.2 ± 0.3) compared to control anaesthesia (°C: 36.4 ± 0.3-37.3 ± 0.2, P<0.05). Haematosis improved undergoing combined anaesthesia (+2%, P<0.05) whereas did not change in control animals. There were no differences in respiratory rate between trial and control protocols. This study demonstrates that the proposed balanced intravenous-inhalant protocol permits to carry out a very effective, stable and safe anaesthesia in swine undergoing deep anaesthesia.

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Section: Discussionmentioning

confidence: 99%

A Novel and Effective Balanced Intravenous-Inhalant Anaesthetic Protocol in Swine by Using Unrestricted Drugs

et al. 2014

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“…Halotan je približno podjednako hipotenzivan anestetik kao i izofl uran i metoksifl uran. Zbog svojih svojstava da sprovodni sistem srca čini osetljivim na aritmogenične efekte kateholamina, kontraindikovano ga je koristiti kod pacijenata koji su skloni pojavi srčanih aritmija (Bednarski, 1989). Azot oksidul deluje kao direktni i indirektni simpatomimetički agens (Kawamura i sar., 1980;Ebert i Kampine , 1989;Ebert, 1990;Sellgren i sar., 1990).…”

Section: Diskusijaunclassified

Cardiovascular Disturbances Related to Prolonged Anesthesia in Dogs

Kosić

Trailović

2011

AVM

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As major surgical procedures, which last longer, are associated with signifi cant hemodynamic changes, it is unclear how much the duration of both anesthesia and surgery has an indipendant effect on the outcomes. In this work the infl uence of six hours’ anesthesia was studied on 10 dogs, under no surgery. Prolonged anesthesia was evaluated by direct blood pressure measurement, ecg monitoring and urine collection. During prolonged anesthesia in dogs, decreases of systolic (SAP) (p<0.05, p<0,01), mean (MAP) (p<0.05) blood pressure, heart rate (p<0.05, p<0.01, p<0.001) and urine output (p<0.01, p<0.001), were signifi cant, but the regularity of heart rhythm was maintained. Although blood pressure is preserved within autoregulatory range, the coexisting values of mean blood pressure and heart rate, and T wave polarity changes, point out to existence of myocardial ischemia.

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Anesthesia for the Emergency Small Animal Patient

Perkowski

2000

Veterinary Clinics of North America: Small Animal Practice

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Anesthesia and Pain Control

Cited by 6 publications

References 592 publications

A Novel and Effective Balanced Intravenous-Inhalant Anaesthetic Protocol in Swine by Using Unrestricted Drugs

A Novel and Effective Balanced Intravenous-Inhalant Anaesthetic Protocol in Swine by Using Unrestricted Drugs

Cardiovascular Disturbances Related to Prolonged Anesthesia in Dogs

Anesthesia for the Emergency Small Animal Patient

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