Angiofibrolipoma. A histologic variant of the lipoma

Kershisnik, W; Dj, McCarthy; O’Donnell, Elizabeth

doi:10.7547/87507315-76-2-67

Cited by 10 publications

(14 citation statements)

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“…8 In humans, there are additional variants of lipoma and infiltrating lipoma. 4,5,10 Here we describe three of those variants: angiolipoma (case Nos. 1 and 4), angiofibrolipoma (case No.…”

mentioning

confidence: 99%

Angiolipomatous Tumors in Dogs and a Cat

Liggett¹,

Frazier²,

Styer³

2002

Vet Pathol

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Abstract. Variants of lipoma are uncommon, although fibrolipoma and infiltrative lipoma have been well documented. This report describes two cases of rare angiolipoma in dogs and the first documentation of angiofibrolipoma and infiltrating angiolipoma in a cat and a dog, respectively. Tumors were solitary, and most were located on the thorax of middle-aged patients. Angiolipomas were composed of mature adipose tissue mixed with variable numbers of blood vessels. In addition to the adipose and vascular components, the angiofibrolipoma contained bundles of collagenous connective tissue. The infiltrative angiolipoma had a primary mass external to the muscle and was histologically similar to a mixed intramuscular hemangioma that was confined to the muscle. Both disrupted bundles of striated muscle and were associated with segmental degeneration and loss of myofibers.

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“…8 In humans, there are additional variants of lipoma and infiltrating lipoma. 4,5,10 Here we describe three of those variants: angiolipoma (case Nos. 1 and 4), angiofibrolipoma (case No.…”

mentioning

confidence: 99%

Angiolipomatous Tumors in Dogs and a Cat

Liggett¹,

Frazier²,

Styer³

2002

Vet Pathol

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“…Angiofibrolipoma histologically consists of mature adipocytes, blood vessels, and bundles of collagenous connective tissue with low to moderate cellularity. It is not encapsulated, but is histologically distinct from surrounding tissue 3,8,10 . Furthermore, because angiofibrolipoma shares the histological features of angiolipoma, fibrin thrombi could be present in its blood vessels.…”

Section: Discussionmentioning

confidence: 99%

“…Based on their histopathological features, lipomas can be classified in different variants 2 . A rare histological variant, angiofibrolipoma, has been described in the English literature 3 . A literature search revealed only seven references of angiofibrolipoma, 3–9 most of which are not English‐language publications.…”

Section: Introductionmentioning

confidence: 99%

Angiofibrolipoma of the oral cavity

Epivatianos

Kolokotronis

Matiakis

et al. 2010

J of Invest & Clin Dent

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We describe an unusual and rare case of a lipoma variant known as angiofibrolipoma. A literature search revealed only a few cases of angiofibrolipoma which were located in different anatomical sites; no case of angiofibrolipoma in the oral cavity has been previously reported. We present and discuss the histopatholological-immunohistological findings and features. Angiofibrolipoma histologically consists of mature adipocytes, blood vessels, and bundles of collagenous connective tissue with low to moderate cellularity. It is not encapsulated, but is histologically distinct from surrounding tissue. Positive immunohistological staining with CD-34 presented a large number of blood vessels of different sizes located between collagen fibers and adipocytes. The treatment of choice for a patient with angiofibrolipoma is surgical excision, which is expected to be curative.

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“…Angiomyolipomas frequently are associated with tuberous sclerosis. Positive Masson's trichrome staining for collagen or negative immunostaining for smooth muscle actin differentiates an angiofibrolipoma from an angiolipoleiomyoma 5 . Angiofibrolipomas are thought to be hamartomas (polyclonal) as opposed to true neoplasms (monoclonal) 2 …”

Section: Discussionmentioning

confidence: 99%

Angiofibrolipoma of the Ear Canal

2005

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This variant of lipoma contains mature adipocytes, blood vessels, and dense collagenous tissue. The physical examination can be misleading, and the diagnosis requires histopathological examination. The patient was treated with complete surgical excision, tympanoplasty, canalplasty, and skin grafting to the external auditory canal. His pure-tone average improved from 37 to 11 dB, and his air-bone gap was closed completely. The lipoma has not recurred in the 6-month period following surgery.

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Angiofibrolipoma. A histologic variant of the lipoma

Cited by 10 publications

References 0 publications

Angiolipomatous Tumors in Dogs and a Cat

Angiolipomatous Tumors in Dogs and a Cat

Angiofibrolipoma of the oral cavity

Angiofibrolipoma of the Ear Canal

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