Animal experiments in biomedical research: Knowledge, self-evaluation and attitudes of biology and medical students

Abstract

Animal experiments in biomedical research are debated in public, within the scientific community and among students. Despite increased efforts to reduce, refine and replace animal experiments, they remain integral components of the job of a biomedical scientist. In Germany, persons must have a university degree and adequate education and training to perform and direct animal experiments. Therefore, training courses such as FELASA (Federation of European Laboratory Animal Science Associations) courses are provided. However, in our experience, students become aware of this very late in their studies when decisions about their future careers have already been made. We initiated this study to have a better understanding of when and how animal experiments should be discussed during university education. We evaluated the knowledge, self-evaluation and attitudes of biology and medical students of different semesters regarding animal experiments at the RWTH Aachen University, Germany. An online survey was conducted to assess demographic information, knowledge about animal experiments, self-evaluation and attitudes towards animal experiments. Students of both fields showed limited knowledge of animal experiments. Biology students showed significantly better knowledge and self-evaluated their knowledge higher than medical students. The field of the study correlated with their knowledge and self-evaluation but did not predict participants’ attitudes towards animal experiments. In conclusion, the current study showed that there is still room for improvement to raise awareness about laboratory animal science in the biomedical research field.

Virtual Reality in Biomedical Education in the sense of the 3Rs

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Exploring plant polyphenols as anti-allergic functional products to manage the growing incidence of food allergy

“…In vivo studies of allergic reactions mainly use animals as experimental subjects. Animal experiments are widely used in life science research and play an important role therein ( 58 ). Guinea pigs, BALB/c mice, Wistar rats, Sprague Dawley rats, Brown Norway rats, piglets, and dogs have been used in experimental anti-allergic studies ( 59 – 65 ).…”