ANTHELMINTIC RESISTANCE IN SMALL RUMINANTS FROM THE SEMIARID OF PARAÍBA STATE, BRAZIL/Resistência anti-helmíntica em pequenos ruminantes do semiárido da Paraíba, Brasil

Melo, Lídio Ricardo Bezerra de; Vilela, Vinícius Longo Ribeiro; Feitosa, Thaís Ferreira; Neto, J. L. Almeida; Morais, Dayana Firmino de

doi:10.15361/2175-0106.2013v29n2p104-108

Cited by 11 publications

(8 citation statements)

References 12 publications

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“…In this region, other researches too showed that that Haemonchus sp. was the most frequent helminth of sheep and goats (LIMA et al, 2010;VILELA et al, 2012b;MELO et al, 2013).…”

Section: Discussionmentioning

confidence: 99%

Control of sheep gastrointestinal nematodes using the combination of Duddingtonia flagrans and Levamisole Hydrochloride 5%

Vilela

Feitosa

Braga

et al. 2018

Rev. Bras. Parasitol. Vet.

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The objective was to evaluate the action of D. flagrans pellets in association with Levamisole Hydrochloride 5% for controlling sheep gastrointestinal nematodes in the northeastern Brazil. Three groups of six sheep each were formed: group 1 received 3 g of the pellets (0.6 g of D. flagrans mycelium) for each 10 kg b.w., twice a week for six months, and deworming with Levamisole Hydrochloride 5% when EPG ≥ 1500; group 2 received a dosage of Levamisole Hydrochloride 5% when EPG ≥ 1500; and group 3 received 3 g of pellets without fungi for each 10 kg b.w., twice a week for six months. EPG counts, larval cultures, packed cell volume (PCV) and weighing were performed every 15 days; monthly, samples of grass from each paddock were collected. The mean EPG of the groups began to statistically differ from day 30 (p < 0.05). Group 1 required less deworming with Levamisole Hydrochloride 5% and showed superiority of PCV values throughout the experiment (p < 0.05). There was a significant reduction (p < 0.05) in L3 recovery in the group 1 paddock from day 30 onwards. The use of D. flagrans pellets in association with Levamisole Hydrochloride 5% was effective for controlling gastrointestinal nematodes.

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“…In this region, other researches too showed that that Haemonchus sp. was the most frequent helminth of sheep and goats (LIMA et al, 2010;VILELA et al, 2012b;MELO et al, 2013).…”

Section: Discussionmentioning

confidence: 99%

Control of sheep gastrointestinal nematodes using the combination of Duddingtonia flagrans and Levamisole Hydrochloride 5%

Vilela

Feitosa

Braga

et al. 2018

Rev. Bras. Parasitol. Vet.

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“…Other research also reported the predominance of Haemonchus sp. in small ruminants in the semi-arid region (Lima et al, 2010;Melo, Vilela, Feitosa, Almeida, & Morais, 2013;Vieira et al, 2014). This parasite directly influences the correct FMC interpretation, which must be of at least 60% prevalence to validate the effectiveness of the method to different categories (Fernandes et al, 2015).…”

Section: Discussionmentioning

confidence: 99%

“…During the short rainy season Haemonchus sp. and Trichostrongylus spp., can cause high infection rates with increasing fecal egg count (FEC) (W. W. Silva, Bevilaqua, & Rodrigues, 2003;Vilela et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Sustainable agriculture: the use of FAMACHA method in Santa Ines sheep in the Semi-arid region of Brazil

Vilela¹,

Bezerra²,

Bezerra³

et al. 2021

Semina: Ciênc. Agrár.

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Sheep farming is of great importance in generating income to smallholders in semi-arid areas worldwide. Gastrointestinal helminths cause important damage to the animals with poor welfare conditions, impacting in local economies. The objective of this work was to evaluate the FAMACHA method (FMC) in a herd of 60 Santa Inês from Paraíba, Brazil, and to compare the data from previous production years. In order to determine anemic sheep, FMC chart was used in biweekly evaluations for 12 months by trained personnel. Blood and fecal samples were collected monthly to determine packed cell volume (PCV), and parasite fecal egg count (FEC), respectively. The animals were divided into: dry, pregnant and lactating ewes, lambs and rams. Haemonchus was the predominant helminth genus (94.7%) during the whole year. There were up to 97% of success on the interpretation of FMC with 90 to 100% efficacy in the treatment decision. Among the 1356 evaluations, in only 40 (3%) were required deworming, being 27 during the rainy season and 13 during the long dry season. A statistically significant correlation (P < 0.01) was observed between FEC and PCV for the dry, lactating, and pregnant categories. The data reports a 94% reduction in deworming, with a greater need for anthelmintic use in lambs and lactating ewes (P < 0.05). Our data validates the use of FMC in Santa Inês sheep, which is considered a local resilient breed in the semi-arid region of Brazil. We recommend that animals should be examined during the rainy season to prevent most of the clinical problems.

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“…In another study involving 35 sheep farms in the state of São Paulo, resistance to albendazole and ivermectin was observed in 100% of the farms studied, while 92% showed resistance to closantel and 53% to levamisole (VERÍSSIMO et al, 2012). High anthelmintic resistance was also reported by Melo et al (2013), when evaluating the efficacy of ivermectin and levamisole in 13 sheep farms in the Agreste of the State of Paraíba, with a reduction of only 30.9% and 93%, respectively. When categorizing properties regarding drug efficacy, it was observed that levamisole was highly effective in 30% of the analyses.…”

Section: Propertymentioning

confidence: 92%

“…Among the most used drugs for parasitic control are benzimidazoles (albendazole, fenbendazole, and oxfendazole), milbemycins (moxidectin), avermectins (ivermectin), imidazothiazoles (levamisole hydrochloride), and salicylanilides (closantel sodium) (BORGES, 2003;VIEIRA et al, 2014). In addition, the anthelmintic resistance by H. contortus was particularly alarming in many studies all over Brazil (SALGADO & SANTOS, 2016), including semi-arid region of the Paraíba State (RODRIGUES et al, 2007;LIMA et al, 2010;MELO et al, 2013;VILELA et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

Nematode resistance to five anthelmintic classes in naturally infected sheep herds in Northeastern Brazil

Silva

Bezerra

Feitosa

et al. 2018

Rev. Bras. Parasitol. Vet.

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This study aimed to evaluate the occurrence of nematode resistance to anthelmintics on sheep herds from the semi-arid region of Paraíba, Northeastern Brazil. Fecal Egg Count Reduction Test (FECRT) was carried out on 20 properties. In each herd, 30 animals were divided into five groups containing six animals each: group I, treated with albendazole 10%, 4 mg/kg; group II, ivermectin 0.08%, 0.2 mg/kg; group III, closantel 10%, 10 mg/kg; group IV, levamisole hydrochloride 5%, 5 mg/kg; and group V, monepantel 2.5%, 2.5 mg/kg. All treatments were administered orally as a single dose. Fecal samples were collected on days zero and 10 after treatment, to perform FECRT and coprocultures. Multiresistance was observed in all the properties; 95% had high resistance to albendazole, 85% to ivermectin, 80% to closantel, 40% to levamisole, and 45% to monepantel. On property 15, where monepantel was ineffective, a second FECRT for this anthelmintic was carried out 4 months after the first, resulting in 75% efficacy. Immediately after the FECRT result, two ewes were euthanized and necropsied, and Haemonchus contortus, Trichostrongylus axei, Trichostrongylus colubriformis, Oesophagostomum columbianum, and Trichuris ovis were recovered. It was concluded that the resistance of sheep gastrointestinal nematodes to antthelmintic, including monepantel, is high.

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ANTHELMINTIC RESISTANCE IN SMALL RUMINANTS FROM THE SEMIARID OF PARAÍBA STATE, BRAZIL/Resistência anti-helmíntica em pequenos ruminantes do semiárido da Paraíba, Brasil

Cited by 11 publications

References 12 publications

Control of sheep gastrointestinal nematodes using the combination of Duddingtonia flagrans and Levamisole Hydrochloride 5%

Control of sheep gastrointestinal nematodes using the combination of Duddingtonia flagrans and Levamisole Hydrochloride 5%

Sustainable agriculture: the use of FAMACHA method in Santa Ines sheep in the Semi-arid region of Brazil

Nematode resistance to five anthelmintic classes in naturally infected sheep herds in Northeastern Brazil

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