Anti-diabetic and anti-obesity: Efficacy evaluation and exploitation of polyphenols in fruits and vegetables

Chen, Luyao; Pu, Yijing; Xu, Ye; He, Xu; Cao, Jiankang; Ma, Yuxia; Jiang, Weibo

doi:10.1016/j.foodres.2022.111202

Cited by 48 publications

(26 citation statements)

References 105 publications

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“…Fruits and vegetables (F&V) are acknowledged as indispensable components of a balanced diet that protects against a host of diseases, entailing obesity, type II diabetes, and heart disease (Chen, Pu et al., 2022; Jiang et al., 2021). Unfortunately, as F&V is more susceptible to spoilage and with a limited shelf life, several researchers are striving to create intelligent packaging systems that can track changes in F&V quality in real time (Müller & Schmid, 2019), comprising colorimetric indicator labels (Chen et al., 2018), bio/chemical sensors (Alam et al., 2021), radio frequency identification (RFID) labels (Ghaani et al., 2016), etc.…”

Section: Classification Of Intelligent Packaging Systems For Fruits A...mentioning

confidence: 99%

A comprehensive review of intelligent packaging for fruits and vegetables: Target responders, classification, applications, and future challenges

Chen

et al. 2023

Comp Rev Food Sci Food Safe

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Post‐harvest fruits and vegetables are extremely susceptible to dramatic and accelerated quality deterioration deriving from their metabolism and adverse environmental influences. Given their vigorous physiological metabolism, monitoring means are lacking due to the extent that unnecessary waste and damage are caused. Numerous intelligent packaging studies have been hitherto carried out to investigate their potential for fruit and vegetable quality monitoring. This state‐of‐the‐art overview begins with recent advances in target metabolites for intelligent packaging of fruits and vegetables. Subsequently, the mechanisms of action between metabolites and packaging materials are presented. In particular, the exact categorization and function of intelligent packaging of fruits and vegetables, are all extensively and comprehensively described. In addition, for the sake of further research in this field, the obstacles that impede the scaling up and commercialization of intelligent packaging for fruits and vegetables are also explored, to present valuable references.

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Section: Classification Of Intelligent Packaging Systems For Fruits A...mentioning

confidence: 99%

A comprehensive review of intelligent packaging for fruits and vegetables: Target responders, classification, applications, and future challenges

Chen

et al. 2023

Comp Rev Food Sci Food Safe

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“…Nani et al [ 98 ] concluded that the overproduction of reactive oxygen species is associated with the inflammatory process in obesity mediated through nuclear factor-κB. Chen et al [ 99 ] reported that polyphenols could enhance the energy consumption and weight loss due to increased fat oxidation. Polyphenols are regarded as being very effective in the inactivation of reactive oxidant species [ 100 ].…”

Section: Novel Drugs In Obesity Treatmentmentioning

confidence: 99%

“…Polyphenols are regarded as being very effective in the inactivation of reactive oxidant species [ 100 ]. Polyphenolic compounds from fruits and vegetables reduce lipid accumulation and enhance intestinal microflora [ 99 ]. The fruits and leaves of some Ericaceae species ( Vaccinium corymbosum, Vaccinium myrtillus, etc.)…”

Section: Novel Drugs In Obesity Treatmentmentioning

confidence: 99%

Pharmacological Treatments and Natural Biocompounds in Weight Management

et al. 2023

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The obesity pandemic is one of society’s most urgent public health concerns. One-third of the global adult population may fall under obese or overweight by 2025, suggesting a rising demand for medical care and an exorbitant cost of healthcare expenditure in the coming years. Generally, the treatment strategy for obese patients is largely patient-centric and needs dietary, behavioral, pharmacological, and sometimes even surgical interventions. Given that obesity cases are rising in adults and children and lifestyle modifications have failed to produce the desired results, the need for medical therapy adjunct to lifestyle modifications is vital for better managing obesity. Most existing or past drugs for obesity treatment target satiety or monoamine pathways and induce a feeling of fullness in patients, while drugs such as orlistat are targeted against intestinal lipases. However, many medications targeted against neurotransmitters showed adverse events in patients, thus being withdrawn from the market. Alternatively, the combination of some drugs has been successfully tested in obesity management. However, the demand for novel, safer, and more efficacious pharmaceutical medicines for weight management does exist. The present review elucidates the current understanding of the available anti-obesity medicines of synthetic and natural origin, their main mechanisms of action, and the shortcomings associated with current weight management drugs.

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“…Thus far, there is no exact clue for the safe consumption of these compounds to treat obesity and other metabolic disorders [ 82 ]. As obesity is a low-grade chronic inflammation causing insulin resistance, PPs can reduce the risk of type 2 diabetes by reducing obesity [ 83 ].…”

Section: Polyphenols In the Prevention And Treatment Of Different Met...mentioning

confidence: 99%

Polyphenols in Metabolic Diseases

et al. 2022

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Polyphenols (PPs) are a large group of phytochemicals containing phenolic rings with two or more hydroxyl groups. They possess powerful antioxidant properties, multiple therapeutic effects, and possible health benefits in vivo and in vitro, as well as reported clinical studies. Considering their free-radical scavenging and anti-inflammatory properties, these substances can be used to treat different kinds of conditions associated with metabolic disorders. Many symptoms of metabolic syndrome (MtS), including obesity, dyslipidemia, atherosclerosis, elevated blood sugar, accelerating aging, liver intoxication, hypertension, as well as cancer and neurodegenerative disorders, are substantially relieved by dietary PPs. The present study explores the bioprotective properties and associated underlying mechanisms of PPs. A detailed understanding of these natural compounds will open up new opportunities for producing unique natural PP-rich dietary and medicinal plans, ultimately affirming their health benefits.

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Anti-diabetic and anti-obesity: Efficacy evaluation and exploitation of polyphenols in fruits and vegetables

Cited by 48 publications

References 105 publications

A comprehensive review of intelligent packaging for fruits and vegetables: Target responders, classification, applications, and future challenges

A comprehensive review of intelligent packaging for fruits and vegetables: Target responders, classification, applications, and future challenges

Pharmacological Treatments and Natural Biocompounds in Weight Management

Polyphenols in Metabolic Diseases

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