Anti-inflammatory activity of extract and fractions from Nepeta sibthorpii Bentham

Miceli, Natalizia; Taviano, Maria Fernanda; Giuffrida, Daniele; Trovato, A.; Τζακου, Ολγα; Galati, E. M.

doi:10.1016/j.jep.2004.11.024

Cited by 97 publications

(64 citation statements)

References 34 publications

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“…A study Previous studies reported a high correlation between the antioxidant capacity and phenolic constituents of methanol extracts from medicinal plants (Miceli et al, 2005;Maisuthisakul et al, 2007;Li et al, 2008;Sagdic et al, 2008). The present results show that N. italica and S. montana exhibit antioxidant properties.…”

Section: Flavonoid Contentssupporting

confidence: 66%

“…Detection was performed at 320 nm for retinol (vitamin A) and retinol acetate, and 215 nm for d-tocopherol, vitamin D, α-tocopherol, α-tocopherol acetate, 202 nm for phytosterols, 265 nm for vitamin K1. Identification of the individual vitamins and phytosterols were performed by frequent comparison with authentic which grow in Central and Southern Europe, North Africa and Central and Southern Asia (Miceli et al, 2005). In Turkey, the genus Nepeta is represented by 44 species, 22 of which are endemic (Davis, 1982;Akpınar et al, 2008).…”

Section: Chromatographic Analysis and Quantification Of Lipid Solublementioning

confidence: 99%

“…They indicated that quercetin and naringenin were not detected in N. cataria. Miceli et al (2005) showed that Nepeta sibthorpii contained rutin (0.091 mg/g). Also, Proestos et al (2006) determined that Origanum dictannus contained 1.3 mg quercetin /100 g dry sample.…”

Section: Antimicrobial Activitymentioning

confidence: 99%

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Some Biological Compounds, Radical Scavenging Capacities and Antimicrobial Activities in the seeds of Nepeta italica L. and Sideritis montana L. subsp. montana from Turkey

et al. 2011

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RESUMENCompuestos biológicos, capacidad atrapadora de radicales libres y actividad antimicrobiana de las semillas de Nepeta italica L. y Sideritis montana L. subsp. montana de Turquía.Este estudio ha determinado algunos compuestos bioló-gicos (ácidos grasos, vitaminas liposolubles, esteroles y flavonoides), capacidad atrapadora de radicales libres, y actividades antimicrobianas de las semillas de Nepeta italica L. y Sideritis montana L. subsp. montana. Se encontró que el áci-do palmítico (C16:0; 8.54±0.13-3.05±0.04%), ácido oleico (C18:1 n9, 22.41±0.8-18.83±0.1%) y α-linolénico (C18:3 n 3;39.56±0.67-77.04±2.07%) eran mayoritarios en ambas semillas de Nepeta italica L. y Sideritis montana L. subsp. montana. Además, se determinó que tanto Nepeta italica L. como Sideritis montana L. subsp. montana contenían estigmasterol (630.07±1.81μg/g; 80,74±0.71μg/g, respectivamente) y ergosterol (11.01±0.14 μg/g; 161.32±0.63 μg/g respectivamente) y esta última además beta-sitosterol (2.93±0.03μg/g). Además, los resultados muestran que Nepeta italica L. contiene morin (37.79±1.09μg/g), catequina (124.39±2.23μg/g) y naringina (475.96±3.57μg/g) y Sideritis montana L. subsp. montana contiene morin (188.41±2.53μg/g), catequina (64.14±1.86μg/g), naringenina (38.34±1.78 μg/g), como principales flavonoides. También, se determinó que los extractos metanólicos de Nepeta itálica L. y Sideritis montana L. subsp. montana fueron eficaces contra los radicales DPPH. Los resultados obtenidos en el presente estudio mostraron que las vitaminas, los flavonoides y los ácidos grasos de los extractos en las semillas de Nepeta itálica L. y Sideritis montana L. subsp. montana impidieron el crecimiento de los microorganismos utilizados en el ensayo, en diferentes proporciones. PALABRAS CLAVE: Ácidos grasos -Actividad antimicrobiana -DPPH radical scavenging actividad -Esteroles

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Section: Flavonoid Contentssupporting

confidence: 66%

Section: Chromatographic Analysis and Quantification Of Lipid Solublementioning

confidence: 99%

See 1 more Smart Citation

Some Biological Compounds, Radical Scavenging Capacities and Antimicrobial Activities in the seeds of Nepeta italica L. and Sideritis montana L. subsp. montana from Turkey

et al. 2011

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“…Sefidkon and Akbarinia (2003) has demonstrated that 4aα-7α-7aβ-nepetalactone and 1, 8-cineole are the main compounds in N. pogonosperma essential oil. Anti-inflammatory effects of these compounds have also been investigated in previous studies (Silva et al 2003;Miceli et al 2005).…”

Section: Introductionmentioning

confidence: 99%

A reliable and efficient protocol for inducing genetically transformed roots in medicinal plant Nepeta pogonosperma

Valimehr

Sanjarian

Sohi

et al. 2014

Physiol Mol Biol Plants

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Nepeta pogonosperma is an important medicinal plant with anti-inflammatory effects. An efficient and reliable transformation system for this plant was developed through optimization of several factors which affected the rate of Agrobacterium rhizogenes mediated transformation. Five bacterial strains, A4, ATCC15834, LBA9402, MSU440 and A13, two explant types, leaves and stems, and several co-cultivation media were examined. The maximum rate of hairy root induction was obtained from stem explants using MSU440 and ATCC15834 bacterial strains. A drastic increase in the frequency of transformation (91 %) was observed when MS medium lacking NH 4 NO 3 , KH 2 PO 4 , KNO 3 and CaCl 2 . Hairy root lines were confirmed by polymerase chain reaction (PCR) using primers of the rolB gene. According to Southern blot analysis, one T-DNA copy was inserted into each of the hairy root lines. In the present study, transgenic hairy roots have been obtained trough genetic transformation by A. rhizogenes harbouring two plasmids, the Ri plasmid and pBI121 binary vector harbouring gus reporter gene. Expression of the gus gene in transgenic hairy root was confirmed by histochemical GUS assay.

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“…The Nepeta menthoides herb is also from the Labiateae family and is known as "Stoechas" in the Azerbaijan region (10). N. menthoides is used as an antiinflammatory (11) and antispasmodic (10) agent. Searches conducted by the researcher showed that no studies have surveyed the efficacy of these plants on the amount of menstrual bleeding.…”

Section: Introductionmentioning

confidence: 99%

The Effects of Lemon balm (Melissa officinalis L.) Alone and in Combination With Nepeta menthoides on the Menstrual Bleeding in Students With Premenstrual Syndrome: A Randomized Controlled Trial

Mirghafourvand

Malakouti

Mohammad‐Alizadeh‐Charandabi

et al. 2016

Iran Red Crescent Med J

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Anti-inflammatory activity of extract and fractions from Nepeta sibthorpii Bentham

Cited by 97 publications

References 34 publications

Some Biological Compounds, Radical Scavenging Capacities and Antimicrobial Activities in the seeds of <i>Nepeta italica</i> L. and <i>Sideritis montana</i> L. subsp. <i>montana</i> from Turkey

Some Biological Compounds, Radical Scavenging Capacities and Antimicrobial Activities in the seeds of <i>Nepeta italica</i> L. and <i>Sideritis montana</i> L. subsp. <i>montana</i> from Turkey

A reliable and efficient protocol for inducing genetically transformed roots in medicinal plant Nepeta pogonosperma

The Effects of Lemon balm (Melissa officinalis L.) Alone and in Combination With Nepeta menthoides on the Menstrual Bleeding in Students With Premenstrual Syndrome: A Randomized Controlled Trial

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