These compounds are reported to have pharmacological activity as antibacterials. 10,11,15 Isolation of bioactive compounds by distillation of essential oils is reported to be able to isolate more volatile bioactive compounds compared to other extraction methods. 16,17,18 Therefore, this research aim is the important of study the bioactive compound profile of teak flower essential oil and test its potential as an antibacterial on Propionibacterium acnes to treat acne. The approach to providing the outcomes of this research objective was carried out by isolating essential oils from teak flowers using steam distillation. The essential oil produced was analyzed using GC-MS (gas chromatography-mass spectrometry). 17 The GCMS results were further analyzed using the Pubchem database (https://pubchem.ncbi.nlm.nih.gov/) 18 and PASS online 19 . These results will provide data about the activity of bioactive compounds in working as antibacterials that eliminate Propionibacterium acnes which causes acne. The antibacterial activity test of teak flower essential oil was carried out using the disc method.
Materials and Methods