Antibacterial activity from Rhanterium adpressum flowers extracts, depending on seasonal variations

Boussoussa, Hadjer; Khacheba, Ihcen; Djeridane, Amar; Mellah, Nabila; Yousfi, Mohamed

doi:10.1016/j.indcrop.2015.12.020

Cited by 7 publications

(5 citation statements)

References 11 publications

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“…These amounts were compared with results of Asteraceae family plants and Rhanterium species described in the literature. Concerning total phenolic content, Rs proved the highest quantity compared to phenolic content of methanolic extract of Rhanterium epapposum (124.26 mg GAE/g extract), butanolic extract of Rhanterium suaveolens (323 mg GAE/g extract), ethyl acetate extract of Rhanterium suaveolens (240 mg GAE/g extract), lipid extract of Rhanterium adpressum (141.2±0.3 mg GAE/g extract), methanolic extract of Rhanterium adpressum flowers (from 5.55±0.177 to 22.8±0.53 mg GAE/g extract), acetonic extract of Rhanterium adpressum flowers (from 8.76±0.33 to 14.2±0.25 mg GAE/g extract) depending on seasonal variations, and other hydro‐ethanolic extracts from Asteraceaeous plants such as Anthemis arvensis (32.32±0.2 mg GAE/g extract), Artemisia campestris (20.38±0.30 mg GAE/g extract), Artemisia herba ‐ alba (13.06±0.40 mg GAE/g extract) and Artemisia arborescens (3.42±0.50 mg GAE/g extract) . Rs presented the highest amount of flavonoids compared to flavonoid content of Rhanterium adpressum stems extracts (0.02 to 3.25 mg QE/g extract), Rhanterium adpressum flowers extracts (0.01 to 4.94 mg QE/g extract), methanolic extract of Rhanterium epapposum (30.2 mg QE/g extract), [23 ] methanolic extract of Algerian Rhanterium suaveolens (0.005 mg QE/g extract), Anthemis arvensis (13.12±0.1 mg QE/g extract), Artemisia campestris (7.46±0.20 mg QE/g extract), Artemisia herba ‐ alba (11.31±0.51 mg QE/g extract) and Artemisia arborescens (3.25±0.31 mg QE/g extract) …”

Section: Resultsmentioning

confidence: 99%

HPLC‐DAD Analysis, Antioxidant and Protective Effects of Tunisian Rhanterium suaveolens against Acetamiprid Induced Oxidative Stress on Mice Erythrocytes

Chelly

Salah

et al. 2019

Chemistry & Biodiversity

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The present study was performed to assess the HPLC-DAD analysis as well as antioxidant and protective effects of Tunisian Rhanterium suaveolens (Rs) against acetamiprid (ACT) induced oxidative stress on mice erythrocytes. The in vitro assays showed that the methanolic extract of Rs has an impressive antioxidant effect proved by testing the total antioxidant and scavenging activities using BCB, DPPH and ABTS assays, respectively. Moreover, qualitative and quantitative analysis using HPLC-DAD revealed the richness of Rs in polyphenols where p-Coumaric, Apigenin-7-glucoside and Ferulic acid were detected as the most abundant polyphenols. In the in vivo experiment, ACT, used as a toxicity model, was given to mice at a dose of 20 mg/kg. The latter was the origin of hemolytic anemia characterized by a significant decrease in red blood cells, hemoglobin and hematocrit levels and an increase in bilirubin, LDH, osmotic fragility, reticulocytes and white blood cells number. Characteristic erythrocyte morphological alterations were also determined as spherocytosis, schistocytosis and dacryocystitis. The oxidative status of ACT-treated mice was also altered manifested by a significant increase in MDA and GSH levels and a decrease in SOD, CAT and GPx activities. When receiving the Rs methanolic extract at a dose of 300 mg/kg, all the parameters cited above were restored in mice. These remarkable corrections could only confirm the important antioxidant effect and the noticeable protective properties that possess Rs owing to its broad range of secondary bioactive metabolites.

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Section: Resultsmentioning

confidence: 99%

HPLC‐DAD Analysis, Antioxidant and Protective Effects of Tunisian Rhanterium suaveolens against Acetamiprid Induced Oxidative Stress on Mice Erythrocytes

Chelly

Salah

et al. 2019

Chemistry & Biodiversity

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“…The highest phenolic content was detected in R adpressum methanolic extracts collected in April and the extracts activity was related to the concentration of phenolic compounds in active extracts. 109 Further analysis has shown a close correlation between antibacterial activity and phenolic content. The lignum of Rhus verniciflua contains high content of phenolic compounds with less urushiols, which suggests efficient antibacterial activity with less toxicity.…”

Section: Biological Activities Of Phenolic Compoundsmentioning

confidence: 95%

“…Boussoussa et al 109 first reported the seasonal changes of phenolic compounds and antibacterial activity on Rhanterium adpressum . The highest phenolic content was detected in R adpressum methanolic extracts collected in April and the extracts activity was related to the concentration of phenolic compounds in active extracts.…”

Section: Biological Activities Of Phenolic Compoundsmentioning

confidence: 99%

“…107 The green tea kombucha presents antibacterial activity against all the bacteria tested and an increased antiproliferative activity against the cancer cell lines, which is attributed to the presence of catechins among the most abundant phenolic compounds and verbascoside as an exclusive compound. 108 Boussoussa et al 109 first reported the seasonal changes of phenolic compounds and antibacterial activity on Rhanterium adpressum. The highest phenolic content was detected in R adpressum methanolic extracts collected in April and the extracts activity was related to the concentration of phenolic compounds in active extracts.…”

Section: Antibacterial Activitymentioning

confidence: 99%

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A Brief Review of Phenolic Compounds Identified from Plants: Their Extraction, Analysis, and Biological Activity

Zhang

Cai

Cheng

et al. 2022

Natural Product Communications

136

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Phenolic compounds are the most abundant secondary metabolites in plants, showing a wide range of distinct biological activities, have received more and more attention in recent years. This review aims to gather and systematize available information on the phenolic compounds from plants by discussing different types of phenolic compounds, extraction, and analysis methods, with an emphasis on their potential biological activities. The research direction and problems that should be paid attention to in the future are also put forward to provide some references for the further study of phenolic compounds.

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“…Among plants scientifically proven to act as therapeutic agents used in phytotherapy and aromatherapy, those belonging to the genus Rhanterium (Asteraceae) deserve a special mention [1–3] . According to the literature, phenolics‐rich extracts of plants from this genus possess remarkable antioxidant activities, as reported for R. adperessum , R. epapposum and Algerian and Tunisian R. suaveolens , [3–5] while a powerful antimicrobial activity is addressed to the corresponding essential oils [2,6–8] . The composition of hydroalcoholic extracts from R. suaveolens collected in Tunisia was recently studied in detail, [9] revealing the presence of numerous cinnamic acids and their derivatives, and of the flavonols kaempferol and quercetin.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Antioxidant, Anti‐Inflammatory and Antityrosinase Potential of Extracts from Different Aerial Parts ofRhanterium suaveolensfrom Tunisia

Chelly

Occhiuto³

et al. 2021

Chemistry & Biodiversity

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The genus Rhanterium (Asteraceae) is a widely distributed medicinal plant throughout western North Africa and some Rhanterium species are used in folk medicine. The aim of research was to investigate methanolic extracts from different parts (flowers, leaves, and stems) of Tunisian Rhanterium suaveolens as potential sources of bioactive products useful for healthy purposes. In particular, were analyzed the phenolic composition of these extracts and their antioxidant, anti‐inflammatory, and anti‐tyrosinase properties. The phytochemical analyses were performed using standard colorimetric procedures, HPLC‐DAD and HPLC‐DAD‐ESI‐MS. Then, several in vitro cell‐free assays have been used to estimate the antioxidant/free radical scavenging capability of the extracts. Moreover, in vitro, and in vivo anti‐melanogenesis activities of these extracts were tested, respectively, with the tyrosinase inhibition assay and the Zebrafish embryo model. Finally, the anti‐inflammatory potential of these extracts in an in vitro model of acute intestinal inflammation in differentiated Caco‐2 cells was evaluated. The R. suaveolens extracts under study appeared particularly rich in flavonols and hydroxycinnamic acids and all extracts appeared endowed with good antioxidant/free radical scavenging properties, being the flower extracts slightly more active than the others. Moreover, R. suaveolens flowers extract was able to inhibit in vitro tyrosinase activity and exhibited bleaching effects on the pigmentation of zebrafish embryos. Furthermore, all extracts showed good anti‐inflammatory activity in intestinal epithelial cells as demonstrated by the inhibition of TNF‐α‐induced gene expression of IL‐6 and IL‐8. R. suaveolens aerial parts may be considered as a potential source of whitening agents, as well as of agents for the treatment of disorders related to oxidative stress and inflammation.

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Antibacterial activity from Rhanterium adpressum flowers extracts, depending on seasonal variations

Cited by 7 publications

References 11 publications

HPLC‐DAD Analysis, Antioxidant and Protective Effects of Tunisian Rhanterium suaveolens against Acetamiprid Induced Oxidative Stress on Mice Erythrocytes

HPLC‐DAD Analysis, Antioxidant and Protective Effects of Tunisian Rhanterium suaveolens against Acetamiprid Induced Oxidative Stress on Mice Erythrocytes

A Brief Review of Phenolic Compounds Identified from Plants: Their Extraction, Analysis, and Biological Activity

Evaluation of Antioxidant, Anti‐Inflammatory and Antityrosinase Potential of Extracts from Different Aerial Parts ofRhanterium suaveolensfrom Tunisia

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