Antibacterial Activity of Celery Leaves (Apium Graveolens L.) Formulated in Toothpaste Against Streptococcus Mutans

Abstract

Objective: The objective of this research was to determine the antibacterial activity of the toothpaste from an extract of celery leaves on Streptococcusmutans.Methods: The toothpaste was formulated with various concentrations of celery leaves, F1 with concentration of extract (6.25%), F2 (12.5%), andF3 (25%). Each formula was tested the physical characteristics and antibacterial activity toward S. mutans. The antibacterial activity was determinedby the agar well diffusion method using brain heart infusion agar plates. Furthermore, the antibacterial activities were assessed by the presence orabsence of inhibition zones after the plates were incubated at 37°C for 24 h.Results: The results from this test illustrate that all toothpastes under study at various concentrations of celery leaves extract exhibited antibacterialactivity. Maximum inhibition zone in antibacterial activity test was shown by F2 (12.5%). Therefore, we can use these toothpastes as naturalantibacterial on prevention of dental caries caused S. mutans.Conclusion: The toothpaste from an extract of celery leaves showed significant antibacterial activity against S. mutans.

Pathogenic and Antimicrobial Properties of Aquatic Extracts of Viscus album and Apium graveolens

“…Regarding Apium graveolens, Genatrika et al 4 tried to utilize its extract as toothpaste to inhibit Streptococcus mutans and it showed significant antibacterial activity against these bacteria, moreover, they showed that it has a protective or disease preventive antibacterial activities.…”

“…Apium graveolens belonging to the family Umbelliferae (English name Celery), is a herbaceous, biennial and branched stem medicinal plant wildly available in various countries, it is ordinarily cultured in the Europe area as a diet yield and it is also grown in Egyptian cities, regions of Kingdom of Saudi Arabia and Algeria 3 . Celery leaves contain flavonoids, tannins and saponins which have antibacterial effects, as the juice of its roots and leaves possess effective biochemical actions 4 . This extract has many medical activities like anticancer, antiinflammatory, anti-bacterial, anti-spasmodic, antihypercholesterolemic, anti-hepatotoxic and analgesic 5 with many types of research that record anti-inflammatory, antibacterial and antifungal effects of essential oil of celery 6,7 .…”

Counselling and Training of Nutritional Snacks Making for Immunity Increasing During Covid 19 Pandemic

“…This plant can be used as a diuretic, for gland stimulation, bile, kidney stones, to regulate the intestines, to increase appetite, and as a prophylaxis for nervous agitation [21]. Other previous studies have also shown that celery has antimicrobial [22], antioxidant [23], cardioprotective [24],…”

Ameliorative effect of celery seed oil against high-fat diet-induced lipotoxic heart disease in rats

“…The bulk of these herbs are utilized as raw plants, and herbs have been used to cure obesity all over the world in recent years. Efficacy and safety of medicinal plants in the treatment of obesity, dyslipidemia, and diabetes mellitus have been studied extensively (Genatrika et al, 2019). One of the annual or perennial plants that grows throughout Europe as well as the tropical and subtropical parts of Africa and Asia is celery (Apium graveolens L), a member of the Apiaceae family.…”