Antibacterial activity of Thai herbal extracts on acne involved microorganism

Niyomkam, Prisana; Kaewbumrung, Sermwut; Kaewnpparat, S.; Panichayupakaranant, Pharkphoom

doi:10.3109/13880200903150443

Cited by 35 publications

(23 citation statements)

References 14 publications

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“…The leaves of this plant are well known for their analgesic and antipyretic activities (Gami et al, 2012;Sehgal et al, 2011). Although several biological activities of M. elengi leaf extracts have been reported, including free radical scavenging (Saha et al, 2008), antibacterial (Niyomkam et al, 2010) and antifungal (Satish et al, 2007) activities, this is the first report of its anti-HIV-1 IN activity. An ethanol extract of M. elengi leaves was therefore subjected to fractionation and isolation of the anti-HIV-1 IN compounds.…”

Section: Resultsmentioning

confidence: 77%

Anti-HIV-1 integrase activity ofMimusops elengileaf extracts

Suedee¹,

Tewtrakul

Panichayupakaranant

2013

Pharmaceutical Biology

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The leaf extract from M. elengi had the strongest anti-HIV-1 IN activity with an IC₅₀ value of 62.1 µg/mL. A bioassay-guided isolation of the active compounds from M. elengi leaf extract resulted in the isolation of active compounds, identified as a mixture of gallocatechin and epigallocatechin. This mixture of gallocatechin and epigallocatechin showed satisfactory anti-HIV-1 IN activity with an IC₅₀ value of 35.0 µM. A flavanol glycoside, mearnsitrin was also isolated but was inactive at a concentration of 100 µM.

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Section: Resultsmentioning

confidence: 77%

Anti-HIV-1 integrase activity ofMimusops elengileaf extracts

Suedee¹,

Tewtrakul

Panichayupakaranant

2013

Pharmaceutical Biology

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“…Antibacterial activity: Antibacterial activity in this study was conducted using diffusion method according to modified Niyomkam et al (2010) research.…”

Section: Methodsmentioning

confidence: 99%

Stability of Epigallocatechin Gallate (EGCG) from Green Tea (Camellia sinensis) and its Antibacterial Activity against Staphylococcus epidermidis ATCC 35984 and Propionibacterium acnes ATCC 6919

Widyaningr¹,

Fudholi²,

Sudarsono³

et al. 2015

Asian J. of Biological Sciences

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One of problem from anti acne cream formula containing Epigallocatechin gallate (EGCG) from green tea leaves is EGCG stability. The EGCG is unstable to heat and easily oxidated. However, EGCG is the main marker substance related to antibacterial activity. This study aimed to determine the EGCG stability and its antibacterial activity. The EGCG stability testing was obtained during extraction process by adding phosphoric acid buffer, pH 4 buffer solution and control. The stability of these groups then tested at 2, 25 and 40°C temperature. Evaluation for absorbance changing by UV-VIS spectrophotometry was obtained during 15 days. After that, EGCG concentration from the three groups were compared using HPLC. Antibacterial activity testing for acne causing bacteria Staphylococcus epidermidis ATCC 35984 was conducted from phosphoric acid and pH 4 buffer solution groups. The result showed that extreme cold temperature decreasing treatment against green tea leaves extract after infundation, pH 4 buffer solution adding and storage at temperature of 2°C produced the highest EGCG concentration namely 60.98% w/w. Besides that, antibacterial activity from the ethyl acetate fraction of green tea leaves extract by using this method produced a good inhibition against P. acnes and S. epidermidis. Moreover, the antibacterial activity against P. acnes was higher than S. epidermis. The adding of pH 4 buffer solution in extraction process produced the highest EGCG concentration than phosphoric acid adding and no buffer adding. The EGCG was stable at the storage temperature of 2°C and 6% ethyl acetate fraction of green tea leaves extract can be used as an anti acne dosage.

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“…The cotton then was swabbed on Mueller Hinton media that had previously been incubated for approximately 2 hours until smooth and thin as possible, then a hole on Mueller Hinton medium was created. The fraction by concentration of 6% was inserted into the plate hole which then incubated at 37°C for 24 hours in aerobic conditions (Niyomkam et al, 2010).…”

Section: The Antibacterial Activitymentioning

confidence: 99%

Antibacterial activity of the dregs of green tea leaves (Camellia sinensis L.) on Staphylococcus epidermidis as causes of acne

Widyaningrum

Badie'ah

Lestari

2017

JoSSE

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The dregs of green tea leaves have not been used until today, it is still considered as a waste that is not useful. It is known that the dregs of the green tea leaves contain Epigallocatechin-3-gallate (EGCG), which is quite high. EGCG has benefits as an antibacterial. The long-term goal of this research is the application of cosmetic preparation products from the dregs of green tea leaves that have effectiveness, stability and high economic value. The specific target of this research is to get the dose and concentration of the dregs of green tea leaves in a stable and effective way as anti-acne against Staphylococcus epidermidis (S. epidermidis). The search of the dregs of green tea leaves is by techniques of infundation of liquid fractions with ethyl acetate, identification of EGCG compound by using HPLC, antibiotics test against S. epidermidis was conducted by diffusion method. The results showed that the content of EGCG of the dregs of green tea leaves was 21.325% w/w, and the concentration of 1% of the dregs of green tea leaves can inhibit the growth of S. epidermidis well.

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Antibacterial activity of Thai herbal extracts on acne involved microorganism

Cited by 35 publications

References 14 publications

Anti-HIV-1 integrase activity ofMimusops elengileaf extracts

Anti-HIV-1 integrase activity ofMimusops elengileaf extracts

Stability of Epigallocatechin Gallate (EGCG) from Green Tea (Camellia sinensis) and its Antibacterial Activity against Staphylococcus epidermidis ATCC 35984 and Propionibacterium acnes ATCC 6919

Antibacterial activity of the dregs of green tea leaves (Camellia sinensis L.) on Staphylococcus epidermidis as causes of acne

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