Antibacterial wound dressing electrospun nanofibrous material from polyvinyl alcohol, honey and Curcumin longa extract

Abstract

In the recent years, the medical sector is getting increasingly interested in the wound dressing materials that contain medicinal herb instead of metal nanoparticles to impart antibacterial or other desirable properties. Herein, a novel multicomponent nanofibrous mat has been successfully prepared by electrospinning technique from a blended solution of polyvinyl alcohol, honey and Curcumin longa (turmeric) extract for potential application as the wound dressing material. Ethyl acetate extraction was followed to obtain the restorative components of turmeric. The fabricated nanofibrous materials were characterized by scanning electron microscope, moisture management tester, bacterial assay and Fourier-transform infrared spectroscopy (FTIR) to evaluate their morphological, moisture, antibacterial and chemical behavior, respectively. Nanofibers of fabricated mat show an average diameter of 340 nm with better moisture management properties compared to polyvinyl alcohol nanomat alone. The agar diffusion method has been used to evaluate the antibacterial activity against Staphylococcus aureus bacteria showing the formation of inhibition zone with a value of 29 mm and 38 mm. The presence of characteristic peaks in Fourier-transform infrared spectra reveals that all the desired components are present in the developed nanofibrous mats.

Green Approach to Develop Bee Pollen-Loaded Alginate Based Nanofibrous Mat

“…In recent years, many researchers have become interested in developing bionanomaterials using bee products [ 4 ]. The use of bee products, such as honey [ 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 ] and propolis [ 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 ], for developing nanofibrous biomedical applications has been studied extensively. Bee pollen is another bee product that may well influence human health.…”

Green Approach to Develop Bee Pollen-loaded Alginate Based Nanocomposite Mat

“…In recent years, many researchers have become interested in developing bionanomaterials using bee products [4]. The use of bee products, such as honey [5][6][7][8][9][10][11][12][13][14][15] and propolis [16][17][18][19][20][21][22][23][24][25], for developing nanofibrous biomedical applications has been studied extensively. Bee pollen is another bee product that may well influence human health.…”

Scope of Natural Plant Extract to Deactivate COVID-19

“…The practice of using medicinal plants to treat human skin including healing of wounds and burn injuries, antifungal, antiviral, antibacterial applications against skin infections has long history and is going on for primary healthcare even in the modern age [18][19][20].…”

“…Usages of metal nanoparticles like as silver, zing in the existing wound dressing materials is not environment friendly due to its toxicity effect [18]. The altrtnative environment friendly similar materials such as licorice, neem, turmeric, honey, nigella etc.…”